Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.55 |
| ▸ | IDH1 | O75874 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301852 | 0.84 | GAA (0.66) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL30065457 | 0.84 | GAA (0.66) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL10536160 | 0.82 | MPO (0.71) | MPOHNF4AIDH1GAAPLA2G10 | |
| SCHEMBL1928182 | 0.82 | HNF4A (0.74) | MPOHNF4AIDH1GAAMAPT | |
| SCHEMBL20576964 | 0.81 | MAPT (0.54) | MPOCYP19A1GAAMAPTSLC5A1 | |
| SCHEMBL644294 | 0.81 | ALOX15 (0.56) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| Dihydrochalcone SCHEMBL2827303 | 0.80 | CYP19A1 (0.80) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| Dihydrochalcone SCHEMBL29359372 | 0.80 | CYP19A1 (0.80) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL10829584 | 0.79 | TSHR (0.63) | CYP19A1GAAMAPTSLC5A1SLC5A2 | |
| SCHEMBL20549727 | 0.79 | MPO (0.67) | MPOHNF4AIDH1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048920-A1 | Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues | MARS, INCORPORATED (US) | 2010-02-25 | — | — | US | disclosed |
| EP-1896443-A1 | PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES | MARS, INCORPORATED (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007002877-A1 | PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES | MARS, INCORPORATED (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048920-A1 | Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues | HAAO, TES, HPD | MPO 810/4885CYP19A1 216/4885HNF4A 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.