Hexylene Glycol

Hexylene Glycol

SCHEMBL367745

CC(O)CC(C)(C)O.OCCCCCCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexylene Glycol SCHEMBL28766222 1.00 LMNA (0.36) LMNAALDH1A1HSD17B10MEN1KMT2A
Hexylene Glycol SCHEMBL10440356 0.98 TDP1 (0.36) LMNAALDH1A1HSD17B10MEN1KMT2A
Hexylene Glycol SCHEMBL14777083 0.93 TDP1 (0.36) ALDH1A1TSHRTDP1CYP1A2CYP3A4
Hexylene Glycol SCHEMBL8519090 0.87 TDP1 (0.40) ALDH1A1TSHRTDP1CYP1A2CYP3A4
Hexylene Glycol SCHEMBL83192 0.87 TDP1 (0.40) ALDH1A1TSHRTDP1CYP1A2CYP3A4
Hexylene Glycol SCHEMBL28213791 0.87 SMN1; SMN2 (0.48) LMNAALDH1A1HSD17B10MEN1KMT2A
Hexylene Glycol SCHEMBL25204926 0.86 TDP1 (0.32) TDP1
Hexylene Glycol SCHEMBL28242900 0.85
Hexylene Glycol SCHEMBL28843625 0.85
Hexylene Glycol SCHEMBL6869929 0.84 MAPK1 (0.39) LMNAALDH1A1TSHRTDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230292765-A1 NEW AGROCHEMICAL FORMULATIONS FOR FUSARICIDIN PRODUCING BACTERIA BASF SE (DE) 2023-09-21 US disclosed
EP-3897704-A1 TOPICAL FORMULATIONS FOR THE DELIVERY OF MICROBIALLY DERIVED MATERIALS Matrisys Bioscience, Inc. (US) 2021-10-27 EP disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
EP-3810079-A1 HAIR DYEING COMPOSITION COMPRISING AN OXIDATION DYE, A SCLEROGLUCAN GUM AND AN ALKALINE AGENT SUCH AS AN AMINO ACID L'OREAL (FR) 2021-04-28 EP disclosed
WO-2020131997-A1 TOPICAL FORMULATIONS FOR THE DELIVERY OF MICROBIALLY DERIVED MATERIALS MATRISYS BIOSCIENCE, INC. (US) 2020-06-25 WO disclosed
WO-2019243513-A1 HAIR DYEING COMPOSITION COMPRISING AN OXIDATION DYE, A SCLEROGLUCAN GUM AND AN ALKALINE AGENT SUCH AS AN AMINO ACID L'OREAL (FR) 2019-12-26 WO disclosed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 US disclosed
US-20190177308-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. 2019-06-13 US disclosed
US-20180273517-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX INC (US) 2018-09-27 US disclosed
EP-3356356-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2018-08-08 EP disclosed
US-7582786-B2 Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease EUKARION INC. (US) 2009-09-01 US disclosed
US-20060149089-A1 Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease EUKARION, INC. 2006-07-06 US disclosed
US-6777381-B1 FORMING EASY BULK HANDLING, STORAGE STABLE, WASH LIQUOR SOLUBLE PASTE CONTAINING ANIONIC SULFONATED SURFACTANT AND CHELANT THE PROCTER & GAMBLE COMPANY 2004-08-17 US disclosed
US-6689803-B2 ADMINISTERING ANTI-MICROTUBULE COMPOUND-CONTAINING, PHARMACEUTICALLY ACCEPTABLE FORMULATION WHEREIN ANTI-MICROTUBULE COMPOUND IS PACLITAXEL FOR THERAPY AND PROPHYLAXIS OF SURGICAL ADHESIONS ANGIOTECH PHARMACEUTICALS, INC. (CA) 2004-02-10 US disclosed
EP-1204734-B1 LIQUID FLUORESCENT WHITENING AGENT FORMULATION CIBA SC HOLDING AG (CH) 2004-01-28 EP disclosed
US-6660705-B1 Mixture of distyrylbiphenyl compound, nonionic surfactant, polyhydroxy compound, glycol and water CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-09 US disclosed
US-20020183380-A1 Compositions and methods for treating or preventing inflammatory diseases ANGIOTECH PHARMACEUTICALS, INC. (CA) 2002-12-05 US disclosed
EP-1204734-A1 LIQUID FLUORESCENT WHITENING AGENT FORMULATION Ciba SC Holding AG (CH) 2002-05-15 EP disclosed
WO-2001012771-A1 LIQUID FLUORESCENT WHITENING AGENT FORMULATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-02-22 WO disclosed
US-4885270-A O-HYDROXY AROMATIC ACID ESTER SENSITIZER, COLOR FORMING LACTONE; THERMAL PRINTING DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230292765-A1 NEW AGROCHEMICAL FORMULATIONS FOR FUSARICIDIN PRODUCING BACTERIA FUS, ERG28, SPOUT1 LMNA 3994/4885ALDH1A1 1564/4885HSD17B10 143/4885
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 LMNA 3784/4885ALDH1A1 3726/4885HSD17B10 3867/4885
US-20190177308-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 LMNA 4164/4885ALDH1A1 3880/4885HSD17B10 3456/4885
US-20180273517-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 LMNA 4164/4885ALDH1A1 3880/4885HSD17B10 3456/4885
US-20060149089-A1 Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease CAT, SOD1, SOD3 LMNA 998/4885ALDH1A1 309/4885HSD17B10 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.