Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366077 | 0.88 | ATM (0.45) | EGFRSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL367766 | 0.87 | L3MBTL1 (0.43) | EGFRSRCSMN1; SMN2KMT2ALMNA | |
| SCHEMBL365021 | 0.86 | SMN1; SMN2 (0.42) | EGFRSRCSMN1; SMN2KMT2ALMNA | |
| SCHEMBL365273 | 0.85 | PLA2G4A (0.45) | EGFRSRCSMN1; SMN2KMT2AMAPT | |
| SCHEMBL365490 | 0.80 | NCEH1 (0.39) | EGFRSRCSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL367750 | 0.80 | ATM (0.43) | EGFRSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL367225 | 0.79 | KMT2A (0.40) | EGFRSRCSMN1; SMN2KMT2ALMNA | |
| SCHEMBL366075 | 0.77 | MAPT (0.35) | EGFRSRCSMN1; SMN2KMT2ALMNA | |
| SCHEMBL367237 | 0.76 | TSHR (0.49) | SMN1; SMN2KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL365176 | 0.75 | ATM (0.45) | KMT2ALMNAMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |