Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | CHKA | P35790 | 8/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325407 | 0.88 | ACHE (0.64) | ALDH1A1KDM4ERAB9ACHKABCHE | |
| Hydrochloric Acid SCHEMBL11637202 | 0.85 | ACHE (0.61) | ALDH1A1KDM4ERAB9ACHKABCHE | |
| Bromide SCHEMBL2831425 | 0.85 | ACHE (0.68) | ALDH1A1CHKABCHEACHELMNA | |
| SCHEMBL15164180 | 0.83 | CHKA (0.83) | ALDH1A1KDM4ERAB9ACHKABCHE | |
| SCHEMBL1824133 | 0.82 | ALDH1A1 (0.75) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| SCHEMBL93665 | 0.80 | CHKA (0.59) | ALDH1A1KDM4ERAB9ACHKABCHE | |
| Hydrochloric Acid SCHEMBL3278043 | 0.80 | ALDH1A1 (0.79) | ALDH1A1KDM4ERAB9ACHKALMNA | |
| Bromide SCHEMBL1757103 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KDM4ERAB9ACHKABCHE | |
| SCHEMBL8863313 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9ACHKABCHE | |
| Bromide SCHEMBL365151 | 0.78 | CHKA (0.61) | ALDH1A1KDM4ERAB9ACHKABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225497-A | ACID CATALYSTS FOR IMIDATION | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | claimed |
| CN-115160213-B | Rheum emodic acid pyridine quaternary ammonium salt compound and synthetic method and application thereof | 丽江师范高等专科学校 | 2024-02-13 | — | — | CN | disclosed |
| US-20230130980-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-10816556-B2 | Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry | THE GEORGE WASHINGTON UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20200292557-A1 | TAILORED NANOPOST ARRAYS (NAPA) FOR LASER DESORPTION IONIZATION IN MASS SPECTROMETRY | UT-BATTELLE, LLC | 2020-09-17 | — | — | US | disclosed |
| US-10585104-B2 | Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry | THE GEORGE WASHINGTON UNIVERSITY (US) | 2020-03-10 | — | — | US | disclosed |
| US-20180222921-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | PREMIER RESEARCH INTERNATIONAL, LLC | 2018-08-09 | — | — | US | disclosed |
| US-9969751-B2 | High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds | TECHFIELDS PHARMA CO., LTD. (CN) | 2018-05-15 | — | — | US | disclosed |
| US-20170227546-A1 | TAILORED NANOPOST ARRAYS (NAPA) FOR LASER DESORPTION IOINZATION IN MASS SPECTROMETRY | THE GEORGE WASHINGTON UNIVERSITY | 2017-08-10 | — | — | US | disclosed |
| WO-2017083520-A1 | ANIMAL THERAPEUTIC AND FEED COMPOSITIONS AND METHODS OF USE | CADENA BIO, INC. (US) | 2017-05-18 | — | — | WO | disclosed |
| US-20120157371-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | PREMIER RESEARCH INTERNATIONAL, LLC | 2012-06-21 | — | — | US | disclosed |
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| US-8044100-B2 | Methods and compositions for treating amyloid-related diseases | BELLUS HEALTH INC. (CA) | 2011-10-25 | — | — | US | disclosed |
| US-20100323917-A1 | TAILORED NANOPOST ARRAYS (NAPA) FOR LASER DESORPTION IONIZATION IN MASS SPECTROMETRY | ENERGY, UNITED STATES DEPARTMENT OF | 2010-12-23 | — | — | US | disclosed |
| US-20100113591-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2010-05-06 | — | — | US | disclosed |
| EP-1836161-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2007-09-26 | — | — | EP | disclosed |
| US-20070010573-A1 | Methods and compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2007-01-11 | — | — | US | disclosed |
| US-20060223855-A1 | reduces or inhibits amyloid fibril formation, organ specific dysfunction (e.g., neurodegeneration), or cellular toxicity | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-10-05 | — | — | US | disclosed |
| WO-2006085149-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | WO | disclosed |
| US-4225497-A | ACID CATALYSTS FOR IMIDATION | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223855-A1 | reduces or inhibits amyloid fibril formation, organ specific dysfunction (e.g., neurodegeneration), or cellular toxicity | APP, IAPP, BACE1 | ALDH1A1 2230/4885KDM4E 4831/4885RAB9A 3228/4885 |
| US-20180222921-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HPGDS | ALDH1A1 3425/4885KDM4E 4312/4885RAB9A 1255/4885 |
| US-20230130980-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HPGDS | ALDH1A1 3425/4885KDM4E 4312/4885RAB9A 1255/4885 |
| US-20100113591-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | APP, PSEN1, PSEN2 | ALDH1A1 2989/4885KDM4E 4713/4885RAB9A 2815/4885 |
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | APP, PSEN1, PSEN2 | ALDH1A1 3131/4885KDM4E 4793/4885RAB9A 3030/4885 |
| US-20070010573-A1 | Methods and compositions for treating amyloid-related diseases | APP, PSEN1, PSEN2 | ALDH1A1 2989/4885KDM4E 4713/4885RAB9A 2815/4885 |
| US-20120157371-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HPGDS | ALDH1A1 3425/4885KDM4E 4312/4885RAB9A 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.