Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819302 | 0.77 | KMT2A (0.57) | NPSR1KMT2AMEN1GAAPOLB | |
| SCHEMBL6819739 | 0.77 | KMT2A (0.57) | NPSR1KMT2AMEN1GAAPOLB | |
| SCHEMBL29778306 | 0.77 | KMT2A (0.57) | NPSR1KMT2AMEN1GAAPOLB | |
| SCHEMBL4430210 | 0.77 | PDK1 (0.43) | NPSR1KMT2AMEN1POLBNR3C2 | |
| SCHEMBL18310644 | 0.75 | ACHE (0.47) | NPSR1KMT2AMEN1HIF1AGAA | |
| SCHEMBL8274364 | 0.75 | ACHE (0.47) | NPSR1KMT2AMEN1HIF1AGAA | |
| SCHEMBL4452422 | 0.74 | NR3C1 (0.49) | NR3C2NR3C1PGR | |
| SCHEMBL16942491 | 0.73 | KMT2A (0.42) | NPSR1KMT2AMEN1HIF1AGAA | |
| SCHEMBL4430202 | 0.72 | TAAR1 (0.44) | HIF1ANR3C2ALDH1A1SMN1; SMN2NR3C1 | |
| SCHEMBL14158802 | 0.72 | L3MBTL1 (0.45) | GAAPPARGPPARAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |