Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 3/20 | 0.30 |
| ▸ | PARL | Q9H300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20672994 | 0.89 | KMT2A (0.30) | — | |
| SCHEMBL1062744 | 0.87 | PARL (0.32) | PARL | |
| SCHEMBL43777 | 0.87 | PARL (0.32) | PARL | |
| SCHEMBL16330094 | 0.86 | ALDH1A1 (0.32) | ALDH1A1MGLL | |
| SCHEMBL7027419 | 0.81 | — | — | |
| SCHEMBL1309141 | 0.80 | — | — | |
| SCHEMBL10052377 | 0.80 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL9228581 | 0.79 | PARL (0.31) | MGLLPARL | |
| SCHEMBL12237280 | 0.79 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL15218253 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1795896-A2 | Method for the identification and relative quantification of proteins based on the selective isolation of RRNK peptides for the simplification of complex mixtures of proteins | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) (CU) | 2007-06-13 | — | — | EP | claimed |
| US-20070128729-A1 | Method for the identification and relative quantification of proteins based on the selective isolation of RRnK peptides for the simplification of complex mixtures of proteins | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-06-07 | — | — | US | claimed |
| EP-1785729-A2 | A method for the selective isolation of multiply-charged peptides applicable in the quantitative proteomics | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) (CU) | 2007-05-16 | — | — | EP | claimed |
| US-20070099304-A1 | Method for the selective isolation of multiply-charged peptides applicable in the quantitative proteomics | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-05-03 | — | — | US | claimed |
| WO-1999032080-A2 | DEVICE FOR TARGETED IMMOBILIZATION OF THE THROMBOGENIC INHIBITOR HIRUDINE ON POLYMER SURFACES | HOECKER HARTWIG (DE) | 1999-07-01 | — | — | WO | claimed |
| US-11591362-B2 | Orthogonal protecting groups for the preparation of stereodefined phosphorothioate oligonucleotides | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-02-28 | — | — | US | disclosed |
| US-20210179658-A1 | ORTHOGONAL PROTECTING GROUPS FOR THE PREPARATION OF STEREODEFINED PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2021-06-17 | — | — | US | disclosed |
| CN-104877127-A | Eight-armed polyethylene glycol derivative, preparation method and related biological substance modified by derivative | XIAMEN SINOPEG BIOTECH CO LTD | 2015-09-02 | — | — | CN | disclosed |
| US-9095623-B2 | Terminally-functionalized conjugates and uses thereof | SMARTCELLS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140121159-A1 | TERMINALLY–FUNCTIONALIZED CONJUGATES AND USES THEREOF | SMARTCELLS, INC. (US) | 2014-05-01 | — | — | US | disclosed |
| EP-1752457-B1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-8623345-B2 | Terminally-functionalized conjugates and uses thereof | Smartcells (US) | 2014-01-07 | — | — | US | disclosed |
| US-6686395-B2 | THERAPY OF A CARDIAC ARRYTHMIA WHICH CAN BE ELIMINATED BY ACTION POTENTIAL PROLONGATION; POTASSIUM CHANNEL MODULATOR | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030171351-A1 | 2'-substituted 1,1'-biphenyl-2-carboxamides, process for their preparation, their use as medicaments, and pharmaceutical preparations comprising them | AVENTIS PHARMA DEUTSCHLAND GMBH | 2003-09-11 | — | — | US | disclosed |
| US-6531495-B1 | Potassium channel | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-03-11 | — | — | US | disclosed |
| EP-1222163-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | Aventis Pharma Deutschland GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001025189-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-12 | — | — | WO | disclosed |
| WO-1999032080-A2 | DEVICE FOR TARGETED IMMOBILIZATION OF THE THROMBOGENIC INHIBITOR HIRUDINE ON POLYMER SURFACES | HOECKER HARTWIG (DE) | 1999-07-01 | — | — | WO | disclosed |
| US-4668797-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-26 | — | — | US | disclosed |
| US-4562202-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179658-A1 | ORTHOGONAL PROTECTING GROUPS FOR THE PREPARATION OF STEREODEFINED PHOSPHOROTHIOATE OLIGONUCLEOTIDES | PCNA, RNGTT, POLL | ALDH1A1 4121/4885MGLL 3200/4885PARL 3783/4885 |
| US-20030171351-A1 | 2'-substituted 1,1'-biphenyl-2-carboxamides, process for their preparation, their use as medicaments, and pharmaceutical preparations comprising them | MLLT3, RYR2, KCNH1 | ALDH1A1 217/4885MGLL 4306/4885PARL 2125/4885 |
| US-20140121159-A1 | TERMINALLY–FUNCTIONALIZED CONJUGATES AND USES THEREOF | NPY1R, NTSR1, GRPR | ALDH1A1 1525/4885MGLL 4603/4885PARL 3416/4885 |
| US-11591362-B2 | Orthogonal protecting groups for the preparation of stereodefined phosphorothioate oligonucleotides | PCNA, RNGTT, POLL | ALDH1A1 4121/4885MGLL 3200/4885PARL 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.