Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663286 | 1.00 | TDP1 (0.46) | TDP1SMN1; SMN2TRPA1TRPV1GPR52 | |
| SCHEMBL368054 | 1.00 | TDP1 (0.46) | TDP1SMN1; SMN2TRPA1TRPV1GPR52 | |
| SCHEMBL4891051 | 0.87 | HTR3A (0.47) | TDP1SMN1; SMN2MAPTMAOBALOX15 | |
| SCHEMBL11382329 | 0.83 | SLC6A4 (0.41) | SMN1; SMN2TRPA1TRPV1GPR52GAA | |
| SCHEMBL11777041 | 0.81 | SMN1; SMN2 (0.49) | TDP1SMN1; SMN2GPR52GAAMAPT | |
| SCHEMBL11777039 | 0.81 | SMN1; SMN2 (0.49) | TDP1SMN1; SMN2GPR52GAAMAPT | |
| SCHEMBL363987 | 0.78 | CYP1A2 (0.45) | TDP1SMN1; SMN2GPR52MAPTL3MBTL1 | |
| SCHEMBL22776005 | 0.78 | HTR3E (0.46) | MAPTL3MBTL1ALDH1A1MAOBALOX15 | |
| SCHEMBL7991942 | 0.78 | TAAR1 (0.45) | TRPA1TRPV1GPR52HTR2ATAAR1 | |
| SCHEMBL4860736 | 0.78 | LPL (0.45) | GAAMAPTL3MBTL1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527165-A4 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | DU PONT (US) | 2006-06-07 | — | — | EP | claimed |
| EP-1527165-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. du Pont de Nemours and Company (US) | 2005-05-04 | — | — | EP | claimed |
| US-20030215929-A1 | Rhodococcus gene encoding aldoxime dehydratase | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-20 | — | — | US | claimed |
| WO-2003078581-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-25 | — | — | WO | claimed |
| JP-3145448-A | — | — | None | — | — | JP | disclosed |
| JP-10251250-A | — | — | None | — | — | JP | disclosed |
| US-12570675-B2 | Boronic acid compounds | LG CHEM, LTD. (KR) | 2026-03-10 | — | — | US | disclosed |
| CN-115160248-B | Kakeromycin and process for producing derivative thereof | 海洋规划生物工厂株式会社 | 2025-03-28 | — | — | CN | disclosed |
| CN-114874131-B | Kakeromycin and process for producing derivative thereof | 海洋规划生物工厂株式会社 | 2025-03-25 | — | — | CN | disclosed |
| CN-114835596-B | Kakeromycin and process for producing derivative thereof | 海洋规划生物工厂株式会社 | 2025-01-17 | — | — | CN | disclosed |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | LG CHEM, LTD. (KR) | 2024-03-28 | — | — | US | disclosed |
| CN-116903480-A | Method for preparing beta-enaminone based on sulfoxide and aldoxime and beta-enaminone | 盐城师范学院 | 2023-10-20 | — | — | CN | disclosed |
| JP-H03145448-A | METHOD FOR PURIFYING BENZYLACETOXIME | DAICEL CHEM IND LTD | 1991-06-20 | — | — | JP | disclosed |
| EP-0334125-A2 | Low density silicone foam | GENERAL ELECTRIC COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4808634-A | KETOXIME ADDITIVE TO REDUCE FOAM DENSITY | GENERAL ELECTRIC COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0281305-A2 | Method for preparing aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1988-09-07 | — | — | EP | disclosed |
| EP-0280499-A2 | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1988-08-31 | — | — | EP | disclosed |
| US-4705878-A | Method for preparing aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1987-11-10 | — | — | US | disclosed |
| US-4705877-A | Novel aminohydrocarbyl-substituted ketoximosilanes | DOW CORNING CORPORATION (US) | 1987-11-10 | — | — | US | disclosed |
| US-4194940-A | THERMOPLASTIC ELASTOMERS BONDED WITH THERMOPLASTIC POLYETHERURETHANE | LORD CORPORATION (US) | 1980-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570675-B2 | Boronic acid compounds | PSMB6, PSMB3, PSMB2 | TDP1 3057/4885SMN1; SMN2 777/4885TRPA1 4633/4885 |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | PSMB11, PSMB1, BACH1 | TDP1 1141/4885SMN1; SMN2 213/4885TRPA1 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.