SCHEMBL3681571

SCHEMBL3681571

O=S(=O)(O)C(F)(Cl)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.39
MMP1 P03956 3/20 0.39
MMP2 P08253 3/20 0.39
MMP9 P14780 3/20 0.39
MMP8 P22894 3/20 0.39
MMP13 P45452 3/20 0.39
F2 P00734 3/20 0.35
PRSS1 P07477 3/20 0.35
PRSS2 P07478 3/20 0.35
PRSS3 P35030 3/20 0.35
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3673939 0.97 CA2 (0.41) CA2CA1MMP1MMP2MMP9
SCHEMBL4376440 0.80 ALDH1A1 (0.39) CA2CA1ALDH1A1L3MBTL1
SCHEMBL25422254 0.77 CA2 (0.34) CA2CA1MMP1MMP2MMP9
Perflubutane SCHEMBL4458683 0.76 CA2 (0.50) CA2CA1MMP1MMP2MMP9
SCHEMBL9098380 0.75 ALDH1A1 (0.39) CA2CA1ALDH1A1L3MBTL1
SCHEMBL3179767 0.75 ALDH1A1 (0.39) CA2CA1ALDH1A1L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL6067738 0.75 CA2 (0.48) CA2CA1MMP1MMP2MMP9
Perflubutane SCHEMBL7865494 0.74 CA2 (0.48) CA2CA1MMP1MMP2MMP9
Perflubutane SCHEMBL1302828 0.74 CA2 (0.48) CA2CA1MMP1MMP2MMP9
Perflubutane SCHEMBL6557063 0.74 TSHR (0.57) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700800-B2 Method for producing fluorine-containing alkyl (meth)acrylate TOKUYAMA CORPORATION (JP) 2010-04-20 US disclosed
US-20090023948-A1 Method for Producing Fluorine-Containing Alkyl (Meth)Acrylate TOKUYAMA CORPORATION (JP) 2009-01-22 US disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed