Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Perflubutane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.48 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | MMP8 | P22894 | 5/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1303190 | 0.97 | CA2 (0.50) | CA2CA1MMP1MMP2MMP9 | |
| Perflubutane SCHEMBL4458683 | 0.96 | CA2 (0.50) | CA2CA1MMP1MMP2MMP9 | |
| Sulfuric Acid SCHEMBL2819379 | 0.93 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| Perflubutane SCHEMBL10729483 | 0.93 | CA2 (0.48) | CA2CA1MMP1MMP2MMP9 | |
| Sulfuric Acid SCHEMBL19348238 | 0.93 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| Perflubutane SCHEMBL7865494 | 0.93 | CA2 (0.48) | CA2CA1MMP1MMP2MMP9 | |
| Perflubutane SCHEMBL28917573 | 0.90 | CA2 (0.46) | CA2CA1MMP1MMP2MMP9 | |
| Sulfuric Acid SCHEMBL19690369 | 0.90 | CA2 (0.50) | CA2CA1MMP1MMP2MMP9 | |
| Perflutren SCHEMBL3944011 | 0.89 | CA5A (0.46) | CA2CA1MMP1MMP2MMP9 | |
| Perflubutane SCHEMBL6557063 | 0.86 | TSHR (0.57) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220073742-A1 | FILLED THERMOPLASTIC COMPOSITIONS HAVING IMPROVED FLOW | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2022-03-10 | — | — | US | claimed |
| EP-3911706-A1 | FILLED THERMOPLASTIC COMPOSITIONS HAVING IMPROVED FLOW | SHPP Global Technologies B.V. (NL) | 2021-11-24 | — | — | EP | claimed |
| CN-113508162-A | Filled thermoplastic composition with improved flowability | 高新特殊工程塑料全球技术有限公司 | 2021-10-15 | — | — | CN | claimed |
| WO-2020148678-A1 | FILLED THERMOPLASTIC COMPOSITIONS HAVING IMPROVED FLOW | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-07-23 | — | — | WO | claimed |
| EP-3683273-A1 | FILLED THERMOPLASTIC COMPOSITIONS HAVING IMPROVED FLOW | SABIC Global Technologies B.V. (NL) | 2020-07-22 | — | — | EP | claimed |
| EP-2525972-B1 | FLAME-PROTECTED ARTICLE HAVING A HIGH LEVEL OF TRANSMISSION | COVESTRO DEUTSCHLAND AG (DE) | 2016-11-02 | — | — | EP | claimed |
| US-20050142371-A1 | Phosphorescent sheets or films having protective topcoat and methods of making the same | RTP COMPANY | 2005-06-30 | — | — | US | claimed |
| US-12617995-B2 | RF heat dissipation plastic, method for manufacturing RF heat dissipation plastic, and repeater cabinet using same | AMOGREENTECH CO., LTD. (KR) | 2026-05-05 | — | — | US | disclosed |
| US-12617994-B2 | Heat-dissipating plastic | AMOGREENTECH CO., LTD. (KR) | 2026-05-05 | — | — | US | disclosed |
| WO-2025121932-A1 | HEAT DISSIPATION WIRED CHARGING MODULE FOR VEHICLE | 주식회사 아모그린텍 | 2025-06-12 | — | — | WO | disclosed |
| US-12302532-B2 | Housing for repeater | AMOGREENTECH CO., LTD. (KR) | 2025-05-13 | — | — | US | disclosed |
| EP-4524200-A1 | TRANSPARENT POLYCARBONATE/POLYACRYLATE BLENDS | Covestro Deutschland AG (DE) | 2025-03-19 | — | — | EP | disclosed |
| CN-119613938-A | Transparent polycarbonate/polyacrylate blends | 科思创德国股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| US-6605659-B2 | Aromatic polycarbonate, rubber modified graft copolymer having a discontinuous rubber phase dispersed in continuous rigid thermoplastic phase, and the group 1A or 2A salt of an aromatic sulfonic acid as flame retardant; moldings | GENERAL ELECTRIC COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-20020120044-A1 | Flame retardant polycarbonate resin/ABS graft copolymer blends | GENERAL ELECTRIC COMPANY | 2002-08-29 | — | — | US | disclosed |
| WO-2002050185-A2 | FLAME RETARDANT POLYCARBONATE RESIN/ABS GRAFT COPOLYMER BLENDS | GENERAL ELECTRIC COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
| US-5693697-A | Flame-resistant polycarbonate moulding-compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-4657955-A | Flameproofing agents, their preparation and their use for flameproofing polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-14 | — | — | US | disclosed |
| US-4615832-A | Flameproofing agents, their preparation and their use for flameproofing polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | disclosed |
| US-4208489-A | AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617994-B2 | Heat-dissipating plastic | HSF1, HSP90AA1, HSPA2 | CA2 4028/4885CA1 1890/4885MMP1 2347/4885 |
| US-12617995-B2 | RF heat dissipation plastic, method for manufacturing RF heat dissipation plastic, and repeater cabinet using same | HSF1, SMC2, SMC3 | CA2 2399/4885CA1 1262/4885MMP1 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.