Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632952 | 0.88 | KCNH3 (0.62) | KCNH3NCF1MAPTALDH1A1HPGD | |
| SCHEMBL28424828 | 0.82 | KCNH3 (0.38) | KCNH3ADRB2NCF1MAPTALDH1A1 | |
| SCHEMBL5556493 | 0.81 | RORC (0.52) | KCNH3NCF1MAPTALDH1A1GAA | |
| SCHEMBL30800855 | 0.81 | ABCB11 (0.49) | KCNH3MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL5013171 | 0.80 | KCNH3 (0.47) | KCNH3NCF1MAPTALDH1A1HPGD | |
| SCHEMBL8264100 | 0.78 | MAPT (0.67) | KCNH3MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL3062486 | 0.78 | KCNH3 (0.65) | KCNH3MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL8260133 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL6571144 | 0.77 | ADRB2 (0.44) | KCNH3ADRB2NCF1MAPTALDH1A1 | |
| SCHEMBL14982724 | 0.77 | KCNH3 (0.51) | KCNH3NCF1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015124233-A1 | COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING ONE OR MORE DIPHENYLAMINE DERIVATIVES, AND USE OF ONE OR MORE DIPHENYLAMINE DERIVATIVES FOR TANNING THE SKIN | BEIERSDORF AG (DE) | 2015-08-27 | — | — | WO | disclosed |
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | KCNH3 4241/4885ADRB2 2242/4885NCF1 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.