Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6554047 | 0.81 | GPR3 (0.34) | — | |
| Hydrochloric Acid SCHEMBL3627628 | 0.77 | GPR3 (0.34) | — | |
| Hydrochloric Acid SCHEMBL4959303 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL5689271 | 0.65 | GPR3 (0.31) | — | |
| SCHEMBL2231523 | 0.65 | ADRA2C (0.40) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL5845700 | 0.63 | ADRA2C (0.36) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| Hydrochloric Acid SCHEMBL6250502 | 0.63 | ADRA2C (0.39) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL2232629 | 0.62 | ADRA2C (0.37) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL9250186 | 0.61 | ALDH1A1 (0.39) | ADRA2CPTGS2HRH1HTR3APDE4D | |
| SCHEMBL22879574 | 0.61 | ADRA2C (0.40) | ADRA2CPTGS2HRH1HTR3APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10150825-B2 | Production method for olefin-based polymer, and olefin polymerization catalyst | IDEMITSU KOSAN CO., LTD. (JP) | 2018-12-11 | — | — | US | disclosed |
| US-20170029539-A1 | PRODUCTION METHOD FOR OLEFIN-BASED POLYMER, AND OLEFIN POLYMERIZATION CATALYST | IDEMITSU KOSAN CO., LTD. (JP) | 2017-02-02 | — | — | US | disclosed |
| EP-1674483-B1 | HIGHER OLEFIN POLYMER HAVING POLAR GROUP AND PROCESS FOR PRODUCING THE SAME | IDEMITSU KOSAN CO (JP) | 2015-03-25 | — | — | EP | disclosed |
| US-8975202-B2 | Polymerization catalysts and method for preservation of same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-03-10 | — | — | US | disclosed |
| US-20120129683-A1 | POLYMERIZATION CATALYSTS AND METHOD FOR PRESERVATION OF SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
| EP-2028198-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containinig the same | IDEMITSU KOSAN CO (JP) | 2010-01-06 | — | — | EP | disclosed |
| EP-1873172-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-1865005-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-7544758-B2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20090124771-A1 | POLYMERIZATION CATALYST AND METHOD FOR PRODUCING POLY-ALPHA-OLEFIN USING THE CATALYST | IDEMITSU KOSAN CO., LTD (JP) | 2009-05-14 | — | — | US | disclosed |
| EP-1865005-A2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | Idemitsu Kosan Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1865006-A2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | Idemitsu Kosan Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1772467-A1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2007-04-11 | — | — | EP | disclosed |
| US-7199202-B2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO. LTD. (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-1095951-B1 | PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME | IDEMITSU KOSAN CO (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-20060293471-A1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1674483-A1 | HIGHER OLEFIN POLYMER HAVING POLAR GROUP AND PROCESS FOR PRODUCING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2006-06-28 | — | — | EP | disclosed |
| US-6906155-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20050043495-A1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-6316561-B1 | POLYMERIZING AN OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST, WHICH COMPRISING DOUBLE-CROSSLINKED TRANSITION METAL COMPLEX TO FORM POLYOLEFIN | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |