SCHEMBL3685401

SCHEMBL3685401

CCCCOc1ccc(C(O)C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
POLB P06746 2/20 0.55
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
PLA2G4B P0C869 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31558760 0.97 LMNA (0.62) LMNAPOLBTP53TSHRMMP9
SCHEMBL9191267 0.95 LMNA (0.64) LMNAPOLBTP53TSHRMMP9
SCHEMBL9193732 0.95 LMNA (0.64) LMNAPOLBTP53TSHRMMP9
SCHEMBL9194774 0.95 LMNA (0.64) LMNAPOLBTP53TSHRMMP9
SCHEMBL9189425 0.95 LMNA (0.64) LMNAPOLBTP53TSHRMMP9
SCHEMBL3685459 0.93 L3MBTL1 (0.53) LMNAPOLBSMN1; SMN2TDP1L3MBTL1
SCHEMBL8323514 0.93 L3MBTL1 (0.53) LMNAPOLBSMN1; SMN2TDP1L3MBTL1
SCHEMBL9380908 0.92 RARB (0.59) LMNAPOLBTP53TSHRMAPK1
SCHEMBL9380903 0.92 RARB (0.59) LMNAPOLBTP53TSHRMAPK1
SCHEMBL9386812 0.87 TDP1 (0.48) LMNAPOLBMAPK1SMN1; SMN2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005420-A Disperse dye for superfine denier fiber and synthesis method thereof 青岛大学 2025-05-16 CN disclosed
US-7737286-B2 α-Hydroxy-benzeneacetic acid derivatives, and compounds having two 5-membered latone rings fused to central cyclohexa-1,4-diene nucleus based upon the same, and uses of the compounds KYUNG-IN SYNTHETIC CORPORATION (KR) 2010-06-15 US disclosed
EP-1663934-A4 ALPHA-HYDROXY-BENZENEACETIC ACID DERIVATIVES, AND COMPOUNDS HAVING TWO 5-MEMBERED LACTONE RINGS FUSED TO CENTRAL CYCLOHEXA-1,4-DIENE NUCLEUS BASED UPON THE SAME, AND USES OF THE COMPOUNDS KYUNG IN SYNTHETIC CORP (KR) 2008-10-01 EP disclosed
US-20070220688-A1 Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds KYUNG-IN SYNTHETIC CORPORATION (KR) 2007-09-27 US disclosed
EP-1663934-A1 ALPHA-HYDROXY-BENZENEACETIC ACID DERIVATIVES, AND COMPOUNDS HAVING TWO 5-MEMBERED LACTONE RINGS FUSED TO CENTRAL CYCLOHEXA-1,4-DIENE NUCLEUS BASED UPON THE SAME, AND USES OF THE COMPOUNDS KYUNG-IN SYNTHETIC CORPORATION (KR) 2006-06-07 EP disclosed
WO-2005028409-A1 ALPHA-HYDROXY-BENZENEACETIC ACID DERIVATIVES, AND COMPOUNDS HAVING TWO 5-MEMBERED LACTONE RINGS FUSED TO CENTRAL CYCLOHEXA-1,4-DIENE NUCLEUS BASED UPON THE SAME, AND USES OF THE COMPOUNDS KYUNG-IN SYNTHETIC CORPORATION (KR) 2005-03-31 WO disclosed
EP-0545861-B1 Diphenylacetic acid derivatives as stabilisers for organic material CIBA GEIGY AG (CH) 1995-12-27 EP disclosed
EP-0545861-A2 Diphenylacetic acid derivatives as stabilisers for organic material CIBA-GEIGY AG (CH) 1993-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070220688-A1 Alpha-Hydroxy-Benzeneacetic Acid Derivatives, and Compounds Having Two 5-Membered Latone Rings Fused to Central Cyclohexa-1,4-Diene Nucleus Based Upon the Same, and Uses of the Compounds LDHA, HCAR1, HPD LMNA 79/4885POLB 2441/4885TP53 1854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.