SCHEMBL3686582

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2052141	0.83	CSF1R (0.40)	TDP1PLA2G2AKMT2ADCTPP1
	SCHEMBL15312704	0.82	CSF1R (0.38)	TDP1PLA2G2ASMN1; SMN2NOS1NOS2
	SCHEMBL2052723	0.82	PLA2G2A (0.44)	GRM2PLA2G2AMAPTMAPK1RAB9A
	SCHEMBL2052185	0.81	LMNA (0.43)	TSHRSMN1; SMN2ALDH1A1MAPTKDM4E
	SCHEMBL31500702	0.81	TDP1 (0.42)	TDP1TSHRHSD17B10SMN1; SMN2NOS1
	SCHEMBL2048637	0.80	CSF1R (0.45)	TDP1ALDH1A1DCTPP1
	SCHEMBL2048708	0.78	KDM4E (0.41)	PLA2G2ASMN1; SMN2ALDH1A1MAPTKDM4E
	SCHEMBL2049433	0.78	LMNA (0.39)	TDP1TSHRHSD17B10PLA2G2ASMN1; SMN2
	SCHEMBL15312793	0.78	ALDH1A1 (0.37)	TDP1TSHRHSD17B10SMN1; SMN2NOS1
	SCHEMBL2051375	0.78	KMT2A (0.40)	SMN1; SMN2ALDH1A1MAPTMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.