Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852063 | 0.86 | TSHR (0.43) | CYP4F2CYP4A11HCAR2TSHRALDH1A1 | |
| SCHEMBL3807287 | 0.85 | CES2 (0.48) | CYP4F2CYP4A11HCAR2THRBCES2 | |
| SCHEMBL16174063 | 0.83 | TSHR (0.45) | CYP4F2CYP4A11HCAR2TSHRALDH1A1 | |
| SCHEMBL8052693 | 0.82 | CYP2C9 (0.42) | CYP2C9CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL7711189 | 0.81 | HSD17B10 (0.34) | HSD17B10HCAR2LMNAALDH1A1THRB | |
| SCHEMBL7632628 | 0.81 | TSHR (0.41) | CYP2C9CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL4961008 | 0.80 | CYP2C9 (0.39) | CYP2C9CYP4F2CYP4A11HSD17B10LMNA | |
| SCHEMBL2562954 | 0.79 | CYP2C9 (0.36) | CYP2C9CYP4F2CYP4A11HSD17B10LMNA | |
| SCHEMBL3687804 | 0.79 | CYP2C9 (0.36) | CYP2C9CYP4F2CYP4A11TSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11068438 | 0.78 | CYP2C9 (0.38) | CYP2C9CYP4F2CYP4A11HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417287-B1 | NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICULAR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF | FUCHS PETROLUB AG (DE) | 2012-12-12 | — | — | EP | claimed |
| US-7101831-B2 | Compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB AG (DE) | 2006-09-05 | — | — | US | claimed |
| US-20030186823-A1 | Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB SE (DE) | 2003-10-02 | — | — | US | claimed |
| US-20130131052-A1 | Amelioration Of The Development Of Cataracts And Other Ophthalmic Diseases | MATIER WILLIAM L (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131052-A1 | Amelioration Of The Development Of Cataracts And Other Ophthalmic Diseases | MATIER WILLIAM L (US) | 2013-05-23 | — | — | US | disclosed |
| US-8383648-B2 | Applying such as 1-oxyl-4-(3'-ethoxy-2',2'-dimethyl)propanecarbonyloxy-2,2,6,6-tetramethylpiperidine to eye surface; halting growth, preventing surgery | COLBY PHARMACEUTICAL COMPANY (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383648-B2 | Applying such as 1-oxyl-4-(3'-ethoxy-2',2'-dimethyl)propanecarbonyloxy-2,2,6,6-tetramethylpiperidine to eye surface; halting growth, preventing surgery | COLBY PHARMACEUTICAL COMPANY (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383648-B2 | Applying such as 1-oxyl-4-(3'-ethoxy-2',2'-dimethyl)propanecarbonyloxy-2,2,6,6-tetramethylpiperidine to eye surface; halting growth, preventing surgery | COLBY PHARMACEUTICAL COMPANY (US) | 2013-02-26 | — | — | US | disclosed |
| EP-1417287-B1 | NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICULAR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF | FUCHS PETROLUB AG (DE) | 2012-12-12 | — | — | EP | disclosed |
| US-7825134-B2 | Amelioration of cataracts, macular degeneration and other ophthalmic diseases | OTHERA HOLDING, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-7825134-B2 | Amelioration of cataracts, macular degeneration and other ophthalmic diseases | OTHERA HOLDING, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-7442711-B2 | Amelioration of the development of cataracts and other ophthalmic diseases | OTHERA HOLDING, INC. (US) | 2008-10-28 | — | — | US | disclosed |
| US-7101831-B2 | Compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB AG (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20050131025-A1 | Amelioration of cataracts, macular degeneration and other ophthalmic diseases | COLBY PHARMACEUTICAL COMPANY | 2005-06-16 | — | — | US | disclosed |
| EP-1417287-A1 | NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICUALR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF | Fuchs Petrolub AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| US-20030186823-A1 | Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB SE (DE) | 2003-10-02 | — | — | US | disclosed |
| WO-2001053438-A1 | NOVEL COMPOSITIONS OF MATERIAL, ESPECIALLY LUBRICANTS AND PRESSURE TRANSMITTING MEANS, THE PRODUCTION AND USE THEREOF | FUCHS PETROLUB AG (DE) | 2001-07-26 | — | — | WO | disclosed |
| EP-0129774-B1 | PROCESS FOR THE PREPARATION OF ALDOLS | BASF Aktiengesellschaft (DE) | 1986-09-10 | — | — | EP | disclosed |
| US-4552985-A | Preparation of aldols | BASF AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | disclosed |
| EP-0129774-A1 | Process for the preparation of aldols | BASF Aktiengesellschaft (DE) | 1985-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186823-A1 | Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | SLC27A2, SLC27A1, ELOVL1 | CYP2C9 2227/4885CYP4F2 1681/4885CYP4A11 1314/4885 |
| US-20130131052-A1 | Amelioration Of The Development Of Cataracts And Other Ophthalmic Diseases | C3AR1, C1R, AKR1C3 | CYP2C9 1154/4885CYP4F2 1332/4885CYP4A11 174/4885 |
| US-20050131025-A1 | Amelioration of cataracts, macular degeneration and other ophthalmic diseases | C1R, CRYAB, C9 | CYP2C9 2207/4885CYP4F2 2422/4885CYP4A11 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.