Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174063 | 0.96 | TSHR (0.45) | TSHRCYP4F2CYP4A11ALDH1A1CES2 | |
| SCHEMBL3807287 | 0.94 | CES2 (0.48) | CYP4F2CYP4A11CES2CES1HCAR2 | |
| SCHEMBL3687624 | 0.86 | CYP2C9 (0.37) | TSHRCYP4F2CYP4A11ALDH1A1CES2 | |
| SCHEMBL15026697 | 0.86 | CYP3A4 (0.55) | TSHRCYP4F2CYP4A11CYP3A4HPGD | |
| SCHEMBL475085 | 0.83 | ALDH1A1 (0.39) | TSHRALDH1A1ATMHCAR2PPARA | |
| SCHEMBL13140448 | 0.83 | TSHR (0.43) | TSHRALDH1A1CES2CES1ATM | |
| SCHEMBL15012918 | 0.83 | CYP4F2 (0.40) | TSHRCYP4F2CYP4A11PPARASMN1; SMN2 | |
| SCHEMBL6863715 | 0.82 | TSHR (0.39) | TSHRALDH1A1CES2CES1ATM | |
| SCHEMBL15026682 | 0.81 | CYP3A4 (0.61) | TSHRCYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL13894974 | 0.81 | TSHR (0.41) | TSHRALDH1A1CES2CES1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417287-B1 | NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICULAR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF | FUCHS PETROLUB AG (DE) | 2012-12-12 | — | — | EP | claimed |
| US-7101831-B2 | Compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB AG (DE) | 2006-09-05 | — | — | US | claimed |
| EP-1016698-B1 | Use of a solvent composition containing an oxyisobutyric acid ester as a solvent in coatings, adhesives and printing inks | MITSUBISHI RAYON CO (JP) | 2004-09-22 | — | — | EP | claimed |
| EP-1417287-A1 | NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICUALR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF | Fuchs Petrolub AG (DE) | 2004-05-12 | — | — | EP | claimed |
| US-20030186823-A1 | Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB SE (DE) | 2003-10-02 | — | — | US | claimed |
| EP-0629671-B1 | Solvent composition | MITSUBISHI RAYON CO (JP) | 2002-03-27 | — | — | EP | claimed |
| WO-2001053438-A1 | NOVEL COMPOSITIONS OF MATERIAL, ESPECIALLY LUBRICANTS AND PRESSURE TRANSMITTING MEANS, THE PRODUCTION AND USE THEREOF | FUCHS PETROLUB AG (DE) | 2001-07-26 | — | — | WO | claimed |
| US-20170240547-A1 | IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS | CHANNEL BIOSCIENCES, LLC | 2017-08-24 | — | — | US | disclosed |
| US-9650376-B2 | Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators | KNOPP BIOSCIENCES LLC (US) | 2017-05-16 | — | — | US | disclosed |
| US-8372859-B2 | CGRP receptor antagonists with tertiary amide, sulfonamide, carbamate and urea end groups | Merck, Sharp & Dohme Corp. (US) | 2013-02-12 | — | — | US | disclosed |
| EP-1417287-B1 | NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICULAR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF | FUCHS PETROLUB AG (DE) | 2012-12-12 | — | — | EP | disclosed |
| US-20100292263-A1 | CGRP RECEPTOR ANTAGONISTS WITH TERTIARY AMIDE, SULFONAMIDE, CARBAMITE AND UREA GROUPS | MERCK SHARP & DOHME LLC | 2010-11-18 | — | — | US | disclosed |
| WO-2008127584-A1 | CGRP RECEPTOR ANTAGONISTS WITH TERTIARY AMIDE, SULFONAMIDE, CARBAMATE AND UREA END GROUPS | MERCK & CO., INC. (US) | 2008-10-23 | — | — | WO | disclosed |
| US-7101831-B2 | Compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB AG (DE) | 2006-09-05 | — | — | US | disclosed |
| EP-1417287-A1 | NOVEL COMPOSITIONS CONTAINING ACETOXYLATED FATTY ACIDS OR FATTY ACID DERIVATES, IN PARTICUALR LUBRICANT AND PRESSURE TRANSMITTING COMPOSITIONS, THE PREPARATION AND USE THEREOF | Fuchs Petrolub AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| US-20030186823-A1 | Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | FUCHS PETROLUB SE (DE) | 2003-10-02 | — | — | US | disclosed |
| WO-2001053438-A1 | NOVEL COMPOSITIONS OF MATERIAL, ESPECIALLY LUBRICANTS AND PRESSURE TRANSMITTING MEANS, THE PRODUCTION AND USE THEREOF | FUCHS PETROLUB AG (DE) | 2001-07-26 | — | — | WO | disclosed |
| EP-0404303-A1 | Glass fiber-reinforced resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0356194-A2 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186823-A1 | Novel compositions of material, especially lubricants and pressure transmitting means, the production and use thereof | SLC27A2, SLC27A1, ELOVL1 | TSHR 4744/4885CYP4F2 1681/4885CYP4A11 1314/4885 |
| US-20170240547-A1 | IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS | KCNA7, KCNA2, KCNK17 | TSHR 1996/4885CYP4F2 451/4885CYP4A11 768/4885 |
| US-20100292263-A1 | CGRP RECEPTOR ANTAGONISTS WITH TERTIARY AMIDE, SULFONAMIDE, CARBAMITE AND UREA GROUPS | CALCR, QRFPR, CALCRL | TSHR 199/4885CYP4F2 2703/4885CYP4A11 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.