SCHEMBL3688359

SCHEMBL3688359

C=C1CC[C@@H]2[C@@H](C1)c1c(OC)cc(C(C)(C)CCCCCC)cc1OC2(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 18/20 1.00
▸ CNR1 P21554 12/20 1.00
▸ NR1I2 O75469 1/20 0.61
▸ ADORA3 P0DMS8 1/20 0.61
▸ SLC6A3 Q01959 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14699456 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL3688362 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL29647952 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31545228 1.00 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL10655727 0.90 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL10655723 0.90 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL11199629 0.90 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL17388420 0.88 CNR2 (0.78) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL17388422 0.88 CNR2 (0.78) CNR2CNR1NR1I2ADORA3SLC6A3
SCHEMBL31545820 0.87 CNR2 (1.00) CNR2CNR1NR1I2ADORA3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 — — US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 — — EP claimed
WO-2025085674-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ULCERATIVE COLITIS BACAINN THERAPEUTICS, INC. (US) 2025-04-24 — — WO claimed
EP-3664795-B1 CANNABIS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN AND INFLAMMATION RELATED WITH DENTAL PULP AND BONE REGENERATION RELATED TO DENTAL JAW BONE DEFECTS CANNIBITE BVBA (BE) 2024-06-19 — — EP claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 — — WO claimed
US-20170014355-A1 CANNABINOID RECEPTOR TREATMENTS TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2017-01-19 — — US claimed
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives TRAVIS CRAIG RICK (US) 2012-11-15 — — US claimed
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation TRAVIS CRAIG RICK (US) 2012-05-17 — — US claimed
US-7763607-B2 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2010-07-27 — — US claimed
US-20080108647-A1 Treatment of HIV and diseases of immune dysregulation TRAVIS CRAIG R 2008-05-08 — — US claimed
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-04-16 — — US disclosed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 — — US disclosed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 — — EP disclosed
US-12421281-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-09-23 — — US disclosed
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-06-05 — — US disclosed
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation TRAVIS CRAIG RICK (US) 2012-05-17 — — US disclosed
US-20110104186-A1 Small molecule immunopotentiators and assays for their detection NOVARTIS VACCINES AND DIAGNOSTICS, INC. 2011-05-05 — — US disclosed
US-20110104186-A1 Small molecule immunopotentiators and assays for their detection NOVARTIS VACCINES AND DIAGNOSTICS, INC. 2011-05-05 — — US disclosed
US-20080312292-A1 Antipruritics YASUI KIYOSHI 2008-12-18 — — US disclosed
WO-2004078261-A1 CANNABINOID RECEPTOR INVERSE AGONISTS AND NEUTRAL ANTAGONISTS AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE DISORDERS THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) 2004-09-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170014355-A1 CANNABINOID RECEPTOR TREATMENTS CNR1, CNR2, GPR18 CNR2 2/4885CNR1 1/4885NR1I2 350/4885
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE ABCC1, SLC47A2, ABCB1 CNR2 350/4885CNR1 723/4885NR1I2 419/4885
US-12421281-B2 Cyclosporine compositions and methods of use FPR2, FPR1, FPR3 CNR2 408/4885CNR1 1097/4885NR1I2 279/4885
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives CNR2, CNR1, GPR18 CNR2 1/4885CNR1 2/4885NR1I2 658/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A CNR2 204/4885CNR1 221/4885NR1I2 3198/4885
US-20080312292-A1 Antipruritics CNR1, CNR2, OPRL1 CNR2 2/4885CNR1 1/4885NR1I2 685/4885
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation CNR2, CNR1, ICOS CNR2 1/4885CNR1 2/4885NR1I2 2189/4885
US-20110104186-A1 Small molecule immunopotentiators and assays for their detection ICOS, CD14, MAVS CNR2 2495/4885CNR1 3003/4885NR1I2 3734/4885
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE FPR2, FPR1, FPR3 CNR2 346/4885CNR1 544/4885NR1I2 214/4885
US-20080108647-A1 Treatment of HIV and diseases of immune dysregulation CNR1, CNR2, ICOS CNR2 2/4885CNR1 1/4885NR1I2 1372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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