Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL3689763 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRCA2L3MBTL1 | |
| SCHEMBL3634656 | 0.90 | RECQL (0.42) | ALDH1A1CYP3A4TSHRCA2L3MBTL1 | |
| SCHEMBL758600 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRCA2L3MBTL1 | |
| Sulfuric Acid SCHEMBL29166273 | 0.87 | TP53 (0.48) | CA2TP53LMNAFDPS | |
| Hydrochloric Acid SCHEMBL2246591 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRCA2L3MBTL1 | |
| Phosphonic Acid SCHEMBL5936022 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRCA2L3MBTL1 | |
| Sulfuric Acid SCHEMBL7812692 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRCA2L3MBTL1 | |
| Lactic Acid SCHEMBL10790158 | 0.80 | CA2 (0.44) | ALDH1A1CYP3A4TSHRCA2L3MBTL1 | |
| SCHEMBL5191874 | 0.79 | LMNA (0.48) | ALDH1A1CYP3A4TSHRL3MBTL1TDP1 | |
| SCHEMBL9807724 | 0.79 | LMNA (0.48) | ALDH1A1CYP3A4TSHRL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016392-A1 | Pesticidal Aggregates | INNOVAFORM TECHNOLOGIES, LLC (US) | 2010-01-21 | — | — | US | claimed |
| EP-2091323-A2 | PESTICIDAL AGGREGATES | Innovaform Technologies, LLC (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008076807-A2 | PESTICIDAL AGGREGATES | INNOVAFORM TECHNOLOGIES, LLC (US) | 2008-06-26 | — | — | WO | claimed |
| US-20100016392-A1 | Pesticidal Aggregates | INNOVAFORM TECHNOLOGIES, LLC (US) | 2010-01-21 | — | — | US | disclosed |
| EP-2091323-A2 | PESTICIDAL AGGREGATES | Innovaform Technologies, LLC (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008076807-A2 | PESTICIDAL AGGREGATES | INNOVAFORM TECHNOLOGIES, LLC (US) | 2008-06-26 | — | — | WO | disclosed |