Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.41 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758600 | 0.98 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL27676851 | 0.88 | LMNA (0.48) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL8327144 | 0.88 | LMNA (0.48) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL5191874 | 0.88 | LMNA (0.48) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL5195412 | 0.88 | LMNA (0.48) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL9807724 | 0.88 | LMNA (0.48) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL8754719 | 0.87 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| Bromide SCHEMBL27824093 | 0.86 | LMNA (0.46) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL21142998 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11419454 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994029266-A1 | SANITIZER FOR SWIMMING POOLS, SPAS, AND HOT TUBS | OLIN CORPORATION (US) | 1994-12-22 | — | — | WO | claimed |
| US-5373025-A | Bactericidal combination of quaternary ammonium compound and copper/ii/ ion source | OLIN CORPORATION (US) | 1994-12-13 | — | — | US | claimed |
| US-5258409-A | REDUCING BACTERIA COUNT IN WATER OF SWIMMING POOLS, HOT TUBS AND SPAS AT HIGH SPEED BY ADDING A QUATERNARY AMMONIUM SALT | OLIN CORPORATION (US) | 1993-11-02 | — | — | US | claimed |
| WO-1993016593-A1 | TREATMENT FOR SANITIZING AQUEOUS SOLUTIONS | OLIN CORPORATION (US) | 1993-09-02 | — | — | WO | claimed |
| EP-2524016-B1 | SURFACTANTS FOR REDUCTION OF WATER BLOCKS AND/OR GAS CONDENSATES AND ASSOCIATED METHODS | HALLIBURTON ENERGY SERV INC (US) | 2014-05-21 | — | — | EP | disclosed |
| EP-2524016-A1 | SURFACTANTS FOR REDUCTION OF WATER BLOCKS AND/OR GAS CONDENSATES AND ASSOCIATED METHODS | Halliburton Energy Services, Inc. (US) | 2012-11-21 | — | — | EP | disclosed |
| US-20110177985-A1 | Surfactants for Reduction of Water Blocks and/or Gas Condensates and Associated Methods | HALLIBURTON ENERGY SERVICES, INC. | 2011-07-21 | — | — | US | disclosed |
| WO-2011086359-A1 | SURFACTANTS FOR REDUCTION OF WATER BLOCKS AND/OR GAS CONDENSATES AND ASSOCIATED METHODS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2011-07-21 | — | — | WO | disclosed |
| US-5490944-A | BLEND OF A QUATERNARY AMMONIUM SALT AND AN AMIDO IMIDAZOLINIUM COMPOUND DISSOLVED IN WATER | COLGATE-PALMOLIVE COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| WO-1994029266-A1 | SANITIZER FOR SWIMMING POOLS, SPAS, AND HOT TUBS | OLIN CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |
| US-5373025-A | Bactericidal combination of quaternary ammonium compound and copper/ii/ ion source | OLIN CORPORATION (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0258923-B1 | FABRIC SOFTENING COMPOSITION AND DETERGENT-COMPOSITION COMPRISING THE SAME | Akzo Nobel N.V. (NL) | 1993-10-06 | — | — | EP | disclosed |
| EP-0258923-A2 | Fabric softening composition and detergent-composition comprising the same | Akzo Nobel N.V. (NL) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258500-A1 | Fabric softening composition and detergent-composition comprising the same | AKZO N.V. (NL) | 1988-03-09 | — | — | EP | disclosed |
| EP-0161262-B1 | QUATERNARY AMMONIUM SALTS USEFUL AS FABRIC SOFTENERS | AKZO N.V. (NL) | 1987-08-12 | — | — | EP | disclosed |
| US-4675118-A | Quaternary ammonium salts useful as fabric softeners | AKZONA INCORPORATED (US) | 1987-06-23 | — | — | US | disclosed |
| US-4569800-A | A TALLOW ALKYL DIMETHYL AMMONIUM SALT; CLEAR AND COLORLESS TRUE SOLUTIONS | AKZONA INCORPORATED (US) | 1986-02-11 | — | — | US | disclosed |
| EP-0161262-A4 | QUATERNARY AMMONIUM SALTS USEFUL AS FABRIC SOFTENERS. | AKZONA INC (US) | 1985-12-05 | — | — | EP | disclosed |
| EP-0161262-A1 | QUATERNARY AMMONIUM SALTS USEFUL AS FABRIC SOFTENERS. | AKZONA INC (US) | 1985-11-21 | — | — | EP | disclosed |
| WO-1985000617-A1 | QUATERNARY AMMONIUM SALTS USEFUL AS FABRIC SOFTENERS | AKZONA INCORPORATED (US) | 1985-02-14 | — | — | WO | disclosed |