Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.47 |
| ▸ | ALPL | P05186 | 5/20 | 0.47 |
| ▸ | XIAP | P98170 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6943796 | 0.98 | TSHR (0.47) | TSHRENPP3ALPLXIAPALDH1A1 | |
| Acetic Acid SCHEMBL10353741 | 0.91 | TSHR (0.50) | TSHRENPP3ALPLXIAPALDH1A1 | |
| Nitric Acid SCHEMBL637677 | 0.88 | NPC1 (0.48) | TSHRENPP3ALPLXIAPALDH1A1 | |
| Nitric Acid SCHEMBL28996492 | 0.86 | NPC1 (0.47) | TSHRENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL22622062 | 0.82 | TSHR (0.52) | TSHRENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL9123767 | 0.81 | ALDH1A1 (0.50) | TSHRENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL3185391 | 0.81 | NOS1 (0.42) | TSHRENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL15459000 | 0.80 | TSHR (0.50) | TSHRENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL6454758 | 0.80 | TSHR (0.50) | TSHRENPP3ALPLXIAPALDH1A1 | |
| Hydrochloric Acid SCHEMBL9124540 | 0.79 | ALDH1A1 (0.49) | TSHRENPP3ALPLXIAPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542889-B1 | LIGAND GUANIDINYL FUNCTIONALIZED POLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2015-03-25 | — | — | EP | claimed |
| EP-2614046-B1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | PROD CHIM AUXILIAIRES ET DE SYNTHESE (FR) | 2014-08-20 | — | — | EP | claimed |
| EP-1357952-B1 | METHOD FOR COATING MEDICAL DEVICE SURFACES | MEDTRONIC INC (US) | 2010-09-01 | — | — | EP | claimed |
| US-6951951-B2 | Process for preparing distamycin derivatives | PHARMACIA ITALIA S.P.A. (IT) | 2005-10-04 | — | — | US | claimed |
| US-6846525-B2 | Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds | XEROX CORPORATION (US) | 2005-01-25 | — | — | US | claimed |
| US-20040202825-A1 | RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS | XEROX CORPORATION | 2004-10-14 | — | — | US | claimed |
| US-20040082759-A1 | Process for preparing distamycin derivatives | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-29 | — | — | US | claimed |
| EP-1183252-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-18 | — | — | EP | claimed |
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | claimed |
| EP-1324983-A1 | PROCESS FOR PREPARING DISTAMYCIN DERIVATIVES | Pharmacia Italia S.p.A. (IT) | 2003-07-09 | — | — | EP | claimed |
| EP-0673783-A2 | Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | claimed |
| EP-0228034-B1 | ARGININE AND AGMATINE DERIVATIVES FOR TREATING PROTOZOAL INFECTIONS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-03 | — | — | EP | claimed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | claimed |
| EP-0127154-B1 | PHARMACEUTICAL PEPTIDES, PREPARATION, USE AND INTERMEDIATES | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-10-03 | — | — | EP | claimed |
| EP-0085963-B1 | PHARMACEUTICAL COMPOUNDS, PREPARATION, USE AND INTERMEDIATES THEREFOR AND THEIR PREPARATION | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-01-21 | — | — | EP | claimed |
| US-4501703-A | Process for preparing 2-acetylthiomethyl-5-guanidinopentanoic acid | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | claimed |
| EP-0127154-A2 | Pharmaceutical peptides, preparation, use and intermediates | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-12-05 | — | — | EP | claimed |
| EP-0085963-A2 | Pharmaceutical compounds, preparation, use and intermediates therefor and their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-08-17 | — | — | EP | claimed |
| US-4208521-A | Process for the preparation of imidazo[2,1-b]quinazolinones | BRISTOL-MYERS COMPANY (US) | 1980-06-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082759-A1 | Process for preparing distamycin derivatives | GSTP1, GSTA1, GSS | TSHR 1554/4885ENPP3 4590/4885ALPL 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.