SCHEMBL36932

SCHEMBL36932

c1ccc(-c2nc3ccccc3nc2-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.55
L3MBTL1 Q9Y468 5/20 0.55
ATM Q13315 1/20 0.55
LMNA P02545 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
GAA P10253 2/20 0.51
ALDH1A1 P00352 3/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
AKT1 P31749 1/20 0.45
AKT2 P31751 1/20 0.45
PKM P14618 1/20 0.44
DHODH Q02127 2/20 0.44
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1303909 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL4883632 0.95 KDM4E (0.52) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL20886601 0.93 L3MBTL1 (0.51) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL12690642 0.91 L3MBTL1 (0.46) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL19655330 0.91 L3MBTL1 (0.50) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL6725348 0.91 L3MBTL1 (0.46) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL11987938 0.91 L3MBTL1 (0.46) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL17759776 0.91 L3MBTL1 (0.50) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL2853353 0.91 L3MBTL1 (0.50) KDM4EL3MBTL1ATMLMNAMEN1
SCHEMBL12690741 0.91 L3MBTL1 (0.46) KDM4EL3MBTL1ATMLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210257559-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-08-19 US disclosed
US-10068533-B2 Liquid crystal display device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-09-04 US disclosed
US-20170186975-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20170186975-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20160225325-A1 LIQUID CRYSTAL DISPLAY DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2016-08-04 US disclosed
US-9349325-B2 Liquid crystal display device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-24 US disclosed
US-9252380-B2 Light-emitting device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-02-02 US disclosed
EP-2366753-B1 Light-Emitting Element and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2015-06-17 EP disclosed
US-8564190-B2 Light-emitting element and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-22 US disclosed
US-20120241794-A1 Light-Emitting Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-27 US disclosed
WO-2012128188-A1 LIGHT-EMITTING DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-09-27 WO disclosed
US-8178216-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 US disclosed
US-8178216-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 US disclosed
US-20110267330-A1 LIQUID CRYSTAL DISPLAY DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-11-03 US disclosed
EP-2366753-A1 Light-Emitting Element and Lighting Device Semiconductor Energy Laboratory Co, Ltd. (JP) 2011-09-21 EP disclosed
US-20110215714-A1 Light-Emitting Element and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-09-08 US disclosed
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-19 US disclosed
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative CRY1, GRK1, CRY2 KDM4E 2006/4885L3MBTL1 826/4885ATM 2120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.