Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 5/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 5/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695804 | 0.91 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8PTGER2 | |
| SCHEMBL3700005 | 0.88 | ALDH1A1 (0.35) | SLC16A3SLC16A1KMT2ALMNAMAPT | |
| SCHEMBL3699028 | 0.87 | PTGDR2 (0.34) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL3700744 | 0.87 | PTGDR2 (0.33) | SLC16A3SLC16A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL3808574 | 0.86 | ABCC9 (0.35) | SLC16A3SLC16A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL4127061 | 0.85 | SLC16A3 (0.34) | SLC16A3SLC16A1KMT2ALMNAHTR6 | |
| SCHEMBL3699813 | 0.84 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8PTGER2 | |
| SCHEMBL3700610 | 0.83 | SLC16A3 (0.33) | SLC16A3SLC16A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL4566348 | 0.83 | PTGER2 (0.33) | ABCC9ABCC8KCNJ11KCNJ8PTGER2 | |
| SCHEMBL3698589 | 0.83 | ALDH1A1 (0.38) | SLC16A3SLC16A1ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |