Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 3/20 | 0.35 |
| ▸ | CASP9 | P55211 | 3/20 | 0.35 |
| ▸ | CYCS | P99999 | 3/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705051 | 0.93 | APAF1 (0.36) | TSHRALDH1A1LMNATP53USP2 | |
| SCHEMBL9101546 | 0.92 | C5AR1 (0.39) | ALDH1A1MAPK1APAF1CASP3CASP9 | |
| SCHEMBL3697424 | 0.91 | APAF1 (0.34) | TSHRALDH1A1LMNATP53USP2 | |
| SCHEMBL3695657 | 0.89 | GLA (0.40) | ALDH1A1GLALMNATP53APAF1 | |
| SCHEMBL3701950 | 0.88 | KCNJ1 (0.36) | TSHRALDH1A1KMT2ALMNATP53 | |
| SCHEMBL3696385 | 0.88 | PTGS2 (0.37) | ALDH1A1APAF1CASP3CASP9CYCS | |
| SCHEMBL3705169 | 0.86 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL3705971 | 0.86 | GLA (0.39) | TSHRALDH1A1GLAMEN1KMT2A | |
| SCHEMBL3708097 | 0.85 | TSHR (0.34) | TSHRALDH1A1TP53USP2NPSR1 | |
| SCHEMBL3697589 | 0.85 | BCHE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040701-B2 | Apaf-1 inhibitor compounds | LABORATORIOS SALVAT, S.A. (ES) | 2015-05-26 | — | — | US | disclosed |
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | LABORATORIOS SALVAT, S.A. (ES) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | APAF1, API5, AIFM1 | TSHR 4570/4885ALDH1A1 701/4885GLA 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.