SCHEMBL370408

SCHEMBL370408

COc1ccc(OC)c(F)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
CA7 P43166 2/20 0.62
CA9 Q16790 2/20 0.62
CA14 Q9ULX7 2/20 0.62
ALDH1A1 P00352 2/20 0.54
KMT2A Q03164 2/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 1/20 0.54
THRB P10828 1/20 0.54
MAPK1 P28482 2/20 0.52
HTT P42858 2/20 0.52
LMNA P02545 1/20 0.52
RAB9A P51151 1/20 0.52
ADRA1A P35348 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
TUBB1 Q9H4B7 3/20 0.50
NFE2L2 Q16236 2/20 0.49
CYP1A1 P04798 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809608 1.00 CA12 (0.62) CA12CA1CA2CA7CA9
Isopropylamine SCHEMBL28069262 0.90 HTR2A (0.54) CA12CA1CA2CA7CA9
SCHEMBL12656891 0.85 LMNA (0.52) CA12CA1CA2CA7CA9
SCHEMBL19722074 0.83 CYP17A1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL1277335 0.83 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL23218 0.83 RAB9A (0.46) CA12CA1CA2CA7CA9
SCHEMBL18355747 0.81 MAPK1 (0.44) CA12CA1CA2CA7CA9
SCHEMBL13785412 0.81 PDE2A (0.47) CA12CA1CA2CA7CA9
SCHEMBL178391 0.81 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL18361620 0.81 TUBB1 (0.53) KMT2AMAPTMAPK1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103456982-A Functional electrolyte for improving charge-discharge efficiency of lithium ion battery and application thereof CHINA NAT OFFSHORE OIL CORP 2013-12-18 CN claimed
CN-101577348-A Multiplex overcharging protection functional electrolyte for lithium ion battery UNIV CENTRAL SOUTH (CN) 2009-11-11 CN claimed
CN-101510622-A Electrolyte for lithium ion secondary battery and battery containing the electrolyte BYD CO LTD (CN) 2009-08-19 CN claimed
US-20260092058-A1 Small Molecule Degraders and Fluorescent Probes of PXR ST JUDE CHILDRENS RES HOSPITAL INC (US) 2026-04-02 US disclosed
US-12516051-B1 Small molecule degraders and fluorescent probes of PXR ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2026-01-06 US disclosed
US-20250282712-A1 DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS ATAI THERAPEUTICS INC (US) 2025-09-11 US disclosed
US-12351537-B2 Dimethoxyphenylalkylamine activators of serotonin receptors ATAI THERAPEUTICS, INC. (US) 2025-07-08 US disclosed
US-20250066309-A1 DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS ROCHE PALO ALTO LLC (US) 2025-02-27 US disclosed
US-20250025462-A1 METHODS OF USING DIAMINOPYRIMIDINE P2X3 AND P2X2/3 RECEPTOR MODULATORS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISEASES ROCHE PALO ALTO LLC (US) 2025-01-23 US disclosed
US-20240294461-A1 DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS Atai Therapeutics Inc. 2024-09-05 US disclosed
CN-113728484-B Electrolyte for lithium secondary battery and lithium secondary battery comprising same 株式会社LG新能源 2024-07-12 CN disclosed
US-5929281-A REACTING A HETROCYCLIC AROMATIC HALIDE WITH AN AMINE COMPOUND IN PRESENCE OF A BASE USING A TRI-TERT-BUTYLPHOSPHINE AND PALLADIUM COMPOUND CATALYST TO FORM HETEROCYCLIC AROMATIC AMINE COMPOUNDS TOSOH CORPORATION (JP) 1999-07-27 US disclosed
US-5849769-A N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection MEDIVIR AB (SE) 1998-12-15 US disclosed
EP-0706514-B1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1998-11-18 EP disclosed
US-5763119-A NEGATIVE AND POSITIVE ELECTRODES FOR ELECTROLYTIC CELLS WITH LITHIUM, CARBON AND DOPES SONY CORPORATION (JP) 1998-06-09 US disclosed
EP-0802173-A1 Process for producing heterocylic aromatic amine or arylamine Tosoh Corporation (JP) 1997-10-22 EP disclosed
CN-1138219-A Non aqueous electroryte secondary cell with shuttle agent SONY CORP (JP) 1996-12-18 CN disclosed
EP-0740359-A1 Non-aqueous electrolyte secondary cell having shuttle agent SONY CORPORATION (JP) 1996-10-30 EP disclosed
EP-0706514-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1996-04-17 EP disclosed
WO-1995006034-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1995-03-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066309-A1 DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS P2RX3, P2RX6, P2RX2 CA12 4606/4885CA1 2902/4885CA2 1106/4885
US-12351537-B2 Dimethoxyphenylalkylamine activators of serotonin receptors HTR1A, HTR7, HTR4 CA12 4851/4885CA1 4634/4885CA2 3235/4885
US-20250025462-A1 METHODS OF USING DIAMINOPYRIMIDINE P2X3 AND P2X2/3 RECEPTOR MODULATORS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISEASES P2RX3, P2RX2, P2RX1 CA12 3683/4885CA1 3217/4885CA2 897/4885
US-20260092058-A1 Small Molecule Degraders and Fluorescent Probes of PXR CRBN, VHL, NR1H4 CA12 1868/4885CA1 715/4885CA2 1061/4885
US-20250282712-A1 DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS HTR1A, HTR7, HTR4 CA12 4851/4885CA1 4634/4885CA2 3235/4885
US-20240294461-A1 DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS HTR1A, HTR7, HTR4 CA12 4851/4885CA1 4634/4885CA2 3235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.