SCHEMBL3706344

SCHEMBL3706344

CC(C)CCOS(C)(=O)=O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
USP2 O75604 2/20 0.55
TSHR P16473 2/20 0.55
KDM4E B2RXH2 1/20 0.55
LMNA P02545 1/20 0.55
MMP9 P14780 1/20 0.55
ALOX15 P16050 1/20 0.55
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
IDO1 P14902 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6653864 0.86 ALDH1A1 (0.46) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL4082038 0.85 ALDH1A1 (0.64) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL7618433 0.84 USP2 (0.55) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL6484412 0.83 LMNA (0.68) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL15220027 0.83 LMNA (0.50) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL11913777 0.83 LMNA (0.50) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL11400795 0.81 LMNA (0.65) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL18419074 0.81 LMNA (0.65) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL12354861 0.81 LMNA (0.65) ALDH1A1USP2TSHRKDM4ELMNA
SCHEMBL3084957 0.81 LMNA (0.65) ALDH1A1USP2TSHRKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264146-B2 Rho kinase inhibitor, method for preparing same and uses thereof BEIJING INCREASE INNOVATIVE DRUG CO., LTD (CN) 2025-04-01 US disclosed
US-12029708-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2024-07-09 US disclosed
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 US disclosed
US-20230159466-A1 INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. 2023-05-25 US disclosed
US-11446261-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2022-09-20 US disclosed
EP-4034107-A1 JAK INHIBITORS Vimalan Biosciences, Inc. (US) 2022-08-03 EP disclosed
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2021-03-18 US disclosed
US-10639286-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2020-05-05 US disclosed
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2019-06-20 US disclosed
US-10188615-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2019-01-29 US disclosed
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA, INC. (US) 2013-08-01 US disclosed
US-20130116296-A1 PYRAZOLE COMPOUND NEUROINNOVATECH APS (DK) 2013-05-09 US disclosed
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-08-23 US disclosed
US-20120129894-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-24 US disclosed
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-17 US disclosed
CN-101889017-A Alkoxy compounds for the treatment of diseases ACUCELA INC 2010-11-17 CN disclosed
US-20090326074-A1 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2009-12-31 US disclosed
EP-2091955-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT Acucela, Inc. (US) 2009-08-26 EP disclosed
WO-2009045479-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. (US) 2009-04-09 WO disclosed
CN-1183778-A Quinolinecarboxylic acid derivs. HOKURIKU PHARMACEUTICAL (JP) 1998-06-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029708-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20130116296-A1 PYRAZOLE COMPOUND HTR2C, HTR3B, HTR3A ALDH1A1 2035/4885USP2 3697/4885TSHR 123/4885
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ALDH1A1 133/4885USP2 3473/4885TSHR 2971/4885
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-11446261-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20090326074-A1 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20230159466-A1 INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF HIF1AN, HIF1A, EGLN2 ALDH1A1 600/4885USP2 788/4885TSHR 3077/4885
US-10188615-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-20120129894-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885
US-12264146-B2 Rho kinase inhibitor, method for preparing same and uses thereof ROCK1, RHOA, ROCK2 ALDH1A1 4142/4885USP2 3930/4885TSHR 3487/4885
US-10639286-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER ALDH1A1 140/4885USP2 3553/4885TSHR 2964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.