Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705439 | 0.88 | TSPO (0.38) | LMNAUSP2F2F10ITGB3 | |
| SCHEMBL3703153 | 0.86 | THRB (0.45) | THRATHRB | |
| SCHEMBL3715784 | 0.85 | TSHR (0.39) | LMNAUSP2F2F10ITGB3 | |
| SCHEMBL3714771 | 0.85 | ESR1 (0.38) | LMNAUSP2F2F10ITGB3 | |
| SCHEMBL3711114 | 0.85 | TSHR (0.44) | LMNATSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL3706682 | 0.84 | THRB (0.39) | LMNAUSP2F2F10ITGB3 | |
| SCHEMBL3710069 | 0.82 | POLB (0.47) | F2F10ITGB3ITGA2BMAPT | |
| SCHEMBL3704908 | 0.82 | MAPT (0.39) | LMNAUSP2F2F10ITGB3 | |
| SCHEMBL3704670 | 0.82 | TSHR (0.40) | MAPTTSHRCYP1A2CYP2D6HPGD | |
| SCHEMBL3704933 | 0.82 | NR3C1 (0.38) | LMNAUSP2F2F10ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |