Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186270 | 0.83 | NPC1 (0.36) | ALDH1A1OPRD1 | |
| SCHEMBL3786553 | 0.82 | RORC (0.32) | RORCALDH1A1OPRD1 | |
| SCHEMBL3710931 | 0.79 | OPRM1 (0.31) | OPRD1 | |
| SCHEMBL3709702 | 0.75 | SLC6A9 (0.41) | RORC | |
| SCHEMBL4243962 | 0.65 | OPRD1 (0.34) | OPRD1 | |
| SCHEMBL3786554 | 0.65 | OPRM1 (0.32) | ALDH1A1OPRD1 | |
| SCHEMBL4181995 | 0.63 | NPC1 (0.36) | OPRD1 | |
| SCHEMBL3711027 | 0.62 | SLC6A9 (0.44) | RORC | |
| SCHEMBL3704054 | 0.61 | SLC6A9 (0.47) | — | |
| SCHEMBL4243958 | 0.60 | OXTR (0.34) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |