Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710286 | 0.93 | MAPT (0.40) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3711048 | 0.93 | ALDH1A1 (0.37) | CTSAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3708502 | 0.88 | IP6K1 (0.40) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL1246421 | 0.87 | SCN9A (0.39) | CTSAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3711309 | 0.86 | FTO (0.36) | ALDH1A1KDM4EHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3704916 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3707761 | 0.86 | DUSP3 (0.35) | CTSAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3705734 | 0.85 | KMO (0.39) | — | |
| SCHEMBL3707271 | 0.84 | PDE4B (0.38) | CTSAADRB2ADRB1ADRB3PDE4B | |
| SCHEMBL2336147 | 0.83 | NR1H4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |