Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707635 | 0.93 | CTSA (0.35) | MAPTALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL3704916 | 0.93 | ALDH1A1 (0.41) | MAPTALDH1A1L3MBTL1CYP1A2KDM4E | |
| SCHEMBL3711048 | 0.86 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3714395 | 0.84 | NR1H4 (0.40) | MAPTALDH1A1HPGDSMN1; SMN2ACR | |
| SCHEMBL3708502 | 0.84 | IP6K1 (0.40) | L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3709682 | 0.83 | FTO (0.39) | MAPTALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL3711309 | 0.83 | FTO (0.36) | ALDH1A1L3MBTL1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3710274 | 0.82 | JMJD6 (0.38) | MAPTKDM4EFTONPC1RAB9A | |
| SCHEMBL3705734 | 0.82 | KMO (0.39) | — | |
| SCHEMBL3707844 | 0.81 | L3MBTL1 (0.38) | MAPTALDH1A1L3MBTL1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |