SCHEMBL3712100

SCHEMBL3712100

CCOC(C)C=C(C)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.33
LMNA P02545 2/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 2/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23469321 0.85
SCHEMBL126033 0.82 LMNA (0.33) LMNAALDH1A1HSD17B10
SCHEMBL465965 0.82 LMNA (0.33) LMNAALDH1A1HSD17B10
SCHEMBL27614377 0.82 ALOX15 (0.34) ALOX15LMNACYP2D6CYP2C9CYP2C19
SCHEMBL24199889 0.79
SCHEMBL7212725 0.78 LMNA (0.31) LMNA
SCHEMBL2197998 0.77 TDP1 (0.31) ALOX15LMNA
SCHEMBL20542144 0.74 ALDH1A1 (0.38) LMNAALDH1A1
SCHEMBL16322664 0.74 ALDH1A1 (0.39) ALDH1A1
SCHEMBL17565591 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12611016-B2 Cationic contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2026-04-28 US claimed
US-12601929-B2 Contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2026-04-14 US claimed
EP-4413404-B1 CATIONIC CONTACT LENS COOPERVISION INT LTD (GB) 2025-10-15 EP claimed
EP-4537135-B1 CONTACT LENS AND PACKAGING SOLUTION COOPERVISION INT LTD (GB) 2025-09-17 EP claimed
EP-4413405-B1 SUSTAINED RELEASE OF OLEIC ACID FROM CONTACT LENSES COOPERVISION INT LTD (GB) 2025-06-18 EP claimed
WO-2025088339-A1 CONTACT LENS WITH TRPM8 AGONIST IS RELEASABLY ADHERED TO THE POLYMERIC LENS BODY COOPERVISION INTERNATIONAL LIMITED (GB) 2025-05-01 WO claimed
US-12282209-B1 Contact lens and packaging solution COOPERVISION INTERNATIONAL LIMITED (GB) 2025-04-22 US claimed
EP-4537135-A1 CONTACT LENS AND PACKAGING SOLUTION CooperVision International Limited (GB) 2025-04-16 EP claimed
EP-4388349-B1 CONTACT LENS COOPERVISION INT LTD (GB) 2025-03-12 EP claimed
CN-116391140-B Cationic contact lens 库博光学国际有限公司 2025-01-10 CN claimed
WO-2022129871-A1 CATIONIC CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-06-23 WO claimed
US-20220183433-A1 CATIONIC CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2022-06-16 US claimed
EP-2681614-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES COOPERVISION INT LTD (GB) 2021-05-05 EP claimed
US-9164298-B2 Wettable silicone hydrogel contact lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2015-10-20 US claimed
US-8865789-B2 Silicone hydrogel contact lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-10-21 US claimed
US-20140022506-A1 Wettable Silicone Hydrogel Contact Lenses COOPER VISION INTERNATIONAL HOLDING COMPANY ,LP (BB) 2014-01-23 US claimed
WO-2012118678-A1 WETTABLE SILICONE HYDROGEL CONTACT LENSES COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-09-07 WO claimed
WO-2012118674-A2 SILICONE HYDROGEL CONTACT LENSES COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-09-07 WO claimed
US-20120220689-A1 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-30 US claimed
EP-2492718-A1 Silicone Hydrogel Contact Lenses CooperVision International Holding Company, LP (BB) 2012-08-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12601929-B2 Contact lens TRPM8, TRPM7, TRPM5 ALOX15 258/4885LMNA 1959/4885CYP2D6 4432/4885
US-12611016-B2 Cationic contact lens SMCHD1, SSB, SMC2 ALOX15 2891/4885LMNA 324/4885CYP2D6 4573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.