SCHEMBL3712426

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18339175	0.86	ALDH1A1 (0.64)	ALDH1A1MAPTSMN1; SMN2HTTHPGD
	SCHEMBL30816665	0.86	ALDH1A1 (0.64)	ALDH1A1MAPTSMN1; SMN2HTTHPGD
	SCHEMBL634399	0.82	ALDH1A1 (0.72)	ALDH1A1MAPTSMN1; SMN2HPGDTDP1
	Hydrochloric Acid SCHEMBL10562751	0.81	ALDH1A1 (0.69)	ALDH1A1MAPTSMN1; SMN2HPGDTDP1
	SCHEMBL9388398	0.79	MAOA (0.52)	ALDH1A1MAPTSMN1; SMN2HTTHPGD
	SCHEMBL6992814	0.79	TDP1 (0.56)	ALDH1A1MAPTSMN1; SMN2HPGDTDP1
	SCHEMBL3701892	0.79	TDP1 (0.56)	ALDH1A1MAPTSMN1; SMN2HPGDTDP1
	SCHEMBL11177962	0.78	HTT (0.58)	ALDH1A1MAPTSMN1; SMN2HTTHPGD
	Bicarbonate SCHEMBL10870596	0.78	TDP1 (0.75)	ALDH1A1MAPTSMN1; SMN2HPGDTDP1
	SCHEMBL28327975	0.77	CNR2 (0.51)	ALDH1A1MAPTSMN1; SMN2HTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.