Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421143 | 0.80 | ADRB2 (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL2304918 | 0.70 | — | — | |
| SCHEMBL1533833 | 0.70 | CHRNB2 (0.30) | CHRNB2CHRNA4 | |
| SCHEMBL15676839 | 0.65 | CHRNB2 (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL726036 | 0.63 | ADRB2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL6631277 | 0.60 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL2051022 | 0.59 | HTR3A (0.57) | CHRNB2CHRNA4 | |
| SCHEMBL9881497 | 0.58 | CHRNB2 (0.54) | CHRNB2CHRNA4 | |
| SCHEMBL20255363 | 0.58 | CHRNB2 (0.54) | CHRNB2CHRNA4 | |
| SCHEMBL22538719 | 0.58 | HTR1A (0.41) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214142-B | Tetracyclic heterocyclic compounds useful as HIV integrase inhibitors | 默沙东公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-2391212-A1 | BRIDGED COMPOUNDS AS HIV INTEGRASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010088167-A1 | BRIDGED COMPOUNDS AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-08-05 | — | — | WO | disclosed |