Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720739 | 0.91 | MAPT (0.39) | MAPTP2RX3SCN9ANPC1RAB9A | |
| SCHEMBL3720648 | 0.88 | MAPT (0.36) | MAPTP2RX3ALDH1A1HPGDTSHR | |
| SCHEMBL3720742 | 0.85 | MAPT (0.37) | MAPTPDE4BP2RX3SCN9ATP53 | |
| SCHEMBL3724494 | 0.83 | MAOA (0.33) | MAPT | |
| SCHEMBL3720723 | 0.83 | MAPT (0.44) | MAPTALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL3722666 | 0.81 | MAOA (0.37) | MAPTHPGD | |
| SCHEMBL3720645 | 0.81 | MAPT (0.39) | MAPTRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL3719669 | 0.80 | PDE4B (0.49) | MAPTPDE4BSCN9AALDH1A1GAA | |
| SCHEMBL3720126 | 0.80 | CRHR1 (0.39) | MAPTP2RX3NPC1RAB9ATP53 | |
| SCHEMBL3717667 | 0.80 | MAPT (0.34) | MAPTP2RX3SCN9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |