Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720292 | 0.86 | MAPT (0.41) | ALDH1A1MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL3725263 | 0.86 | MAPT (0.42) | ALDH1A1RAB9AATMMEN1CYP1A2 | |
| SCHEMBL3726852 | 0.84 | P2RX3 (0.43) | ALDH1A1ATMKMT2AMAPTTRPV1 | |
| SCHEMBL3720114 | 0.81 | MAPT (0.46) | ALDH1A1RAB9ACYP2C9CYP2C19MAPT | |
| SCHEMBL3721863 | 0.81 | MAPT (0.39) | ALDH1A1RAB9AATMMAPTPOLB | |
| SCHEMBL3716747 | 0.81 | MAPT (0.39) | ATMCYP1A2CYP2C19MAPTPOLB | |
| SCHEMBL3717827 | 0.81 | ALDH1A1 (0.49) | ALDH1A1RAB9AATMMEN1CYP1A2 | |
| SCHEMBL3718215 | 0.80 | PIK3CA (0.40) | MAPTBLML3MBTL1 | |
| SCHEMBL3720087 | 0.80 | MAPT (0.38) | MAPTKDM4CKDM4E | |
| SCHEMBL3720134 | 0.80 | ALDH1A1 (0.48) | ALDH1A1RAB9AATMMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |