Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104735 | 0.83 | SCN4A (0.48) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL18698345 | 0.81 | FFAR4 (0.36) | SCN4ACYP3A4CA1CA2CA7 | |
| SCHEMBL1335753 | 0.78 | KMT2A (0.41) | SCN4ASCN9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16606241 | 0.75 | SCN4A (0.42) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL14409292 | 0.73 | ACHE (0.44) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL12440951 | 0.73 | ALDH1A1 (0.44) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL9945947 | 0.73 | LMNA (0.41) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL15183452 | 0.73 | TRPA1 (0.46) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL16572835 | 0.73 | KDM4E (0.45) | SCN4ALMNASCN1ASCN5ASCN9A | |
| SCHEMBL14900773 | 0.73 | CA1 (0.49) | MYCCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |