Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962854 | 0.89 | VNN1 (0.56) | ATMGAAHPGDL3MBTL1TDP1 | |
| SCHEMBL21171923 | 0.83 | ATM (0.54) | ATMGAAHPGDL3MBTL1TDP1 | |
| SCHEMBL7790183 | 0.83 | EGFR (0.46) | ATMNPC1RAB9ALMNA | |
| SCHEMBL3715955 | 0.79 | SIGMAR1 (0.56) | ATMGAATDP1HTTVNN1 | |
| SCHEMBL7796993 | 0.79 | ALDH1A1 (0.53) | HPGDL3MBTL1HTTALDH1A1NPC1 | |
| SCHEMBL8619264 | 0.78 | CES1 (0.64) | GAAL3MBTL1TDP1HTTALDH1A1 | |
| SCHEMBL3286619 | 0.77 | HDAC3 (0.61) | ATMGAAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL2342367 | 0.77 | MAPT (0.62) | ATML3MBTL1TDP1CES2CES1 | |
| SCHEMBL8664876 | 0.77 | HDAC1 (0.67) | GAAHPGDL3MBTL1TDP1TRPV1 | |
| SCHEMBL4582402 | 0.77 | CES1 (0.52) | ATMGAAHPGDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139707-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-09 | — | — | WO | disclosed |