Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 13/20 | 0.42 |
| ▸ | ACACB | O00763 | 9/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720218 | 0.87 | DUT (0.43) | ACACAACACBMCHR1 | |
| SCHEMBL3720196 | 0.84 | ACACA (0.61) | ACACAACACB | |
| SCHEMBL13077234 | 0.83 | ACACB (0.51) | ACACAACACB | |
| SCHEMBL3720103 | 0.83 | ACACB (0.54) | ACACAACACB | |
| SCHEMBL13077049 | 0.83 | ACACB (0.54) | ACACAACACB | |
| SCHEMBL3728782 | 0.80 | ACACA (0.56) | ACACAACACB | |
| SCHEMBL3719950 | 0.78 | MTNR1A (0.38) | ACACAACACBMCHR1 | |
| SCHEMBL3719580 | 0.75 | ACACB (0.38) | ACACAACACBMCHR1 | |
| SCHEMBL3726999 | 0.74 | GPR4 (0.39) | ACACAACACB | |
| SCHEMBL3720087 | 0.74 | MAPT (0.38) | ACACAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |