Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720024 | 0.84 | PDE4B (0.53) | PDE4BHPGDSSCN9A | |
| SCHEMBL3722765 | 0.83 | ACACB (0.45) | SCN9A | |
| SCHEMBL3718481 | 0.82 | PDE4B (0.54) | PDE4BHPGDSSCN9ASCN10ACYP3A4 | |
| SCHEMBL3722768 | 0.81 | MTNR1A (0.50) | SCN9A | |
| SCHEMBL3721952 | 0.80 | SCN9A (0.37) | HCAR3SCN9ASCN10A | |
| SCHEMBL3720074 | 0.80 | JAK2 (0.36) | HCAR3SCN9A | |
| SCHEMBL3720129 | 0.80 | ACACB (0.37) | HCAR3SCN9A | |
| SCHEMBL3723898 | 0.79 | PDE4B (0.50) | PDE4B | |
| SCHEMBL3725359 | 0.79 | PDE4B (0.49) | PDE4BHPGDSSCN9ASCN10A | |
| SCHEMBL3724294 | 0.78 | PDE4B (0.55) | PDE4BSCN9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |