Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.37 |
| ▸ | ACACA | Q13085 | 7/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720074 | 0.88 | JAK2 (0.36) | SCN9AHCAR3MAPT | |
| SCHEMBL3721953 | 0.85 | SCN9A (0.36) | ACACBACACASCN9A | |
| SCHEMBL3726251 | 0.84 | SCN9A (0.33) | ACACBACACASCN9A | |
| SCHEMBL3722768 | 0.82 | MTNR1A (0.50) | ACACBACACASCN9A | |
| SCHEMBL3719910 | 0.82 | PPARG (0.37) | ACACBACACASCN9A | |
| SCHEMBL3720127 | 0.80 | PDE4B (0.49) | SCN9AHCAR3 | |
| SCHEMBL3723899 | 0.80 | KCNH3 (0.36) | SCN9AMAPT | |
| SCHEMBL3725360 | 0.79 | ACACB (0.47) | ACACBACACASCN9A | |
| SCHEMBL3721952 | 0.79 | SCN9A (0.37) | SCN9AHCAR3 | |
| SCHEMBL3719990 | 0.79 | LMNA (0.37) | ACACBSCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |