Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | TEC | P42680 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725263 | 0.90 | MAPT (0.42) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2A6 | |
| SCHEMBL3716841 | 0.84 | MTNR1A (0.54) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3717019 | 0.82 | CYP1A2 (0.43) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2A6 | |
| SCHEMBL3720524 | 0.82 | SMN1; SMN2 (0.39) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2A6 | |
| SCHEMBL3722574 | 0.81 | SCN9A (0.36) | MAPTKDRMAPK14TNNI3KBRAF | |
| SCHEMBL3722368 | 0.81 | HTT (0.52) | RAB9ASMN1; SMN2NPC1CYP1A2MAPT | |
| SCHEMBL3716766 | 0.81 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2A6 | |
| SCHEMBL3722417 | 0.79 | MEN1 (0.38) | RAB9ASMN1; SMN2NPC1MAPTPDE4B | |
| SCHEMBL3717824 | 0.79 | ALDH1A1 (0.45) | RAB9ASMN1; SMN2NPC1CYP1A2MAPT | |
| SCHEMBL3721863 | 0.78 | MAPT (0.39) | RAB9ASMN1; SMN2NPC1MAPTPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |