Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726999 | 0.88 | GPR4 (0.39) | SCN7ASLC6A2SLC6A4SLC6A3ACACA | |
| SCHEMBL3720089 | 0.86 | TEC (0.37) | SCN7ASLC6A2SLC6A4SLC6A3ACACA | |
| SCHEMBL3719580 | 0.86 | ACACB (0.38) | SCN7ASLC6A2SLC6A4SLC6A3ACACA | |
| SCHEMBL3717025 | 0.81 | PARP10 (0.40) | SCN7AKCNH2PARP15PARP10ACACB | |
| SCHEMBL3722876 | 0.81 | ACACB (0.41) | SCN7AKCNH2PARP15PARP10ACACB | |
| SCHEMBL3721867 | 0.80 | SCN7A (0.37) | SCN7ASLC6A2SLC6A4SLC6A3ACACA | |
| SCHEMBL3719950 | 0.79 | MTNR1A (0.38) | SCN7AACACAKCNH2MCHR1ACACB | |
| SCHEMBL3720199 | 0.79 | MTNR1A (0.52) | ACACAMCHR1ACACB | |
| SCHEMBL3727742 | 0.78 | P2RX3 (0.40) | SCN7AACACAKCNH2PARP15PARP10 | |
| SCHEMBL3720087 | 0.78 | MAPT (0.38) | SCN7ASLC6A2SLC6A4SLC6A3ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |