Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.34 |
| ▸ | KYNU | Q16719 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | MMP16 | P51512 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453682 | 0.80 | KEAP1 (0.42) | CA1CA2CA4KEAP1NFE2L2 | |
| SCHEMBL3423871 | 0.73 | KEAP1 (0.49) | CA1CA2KEAP1NFE2L2 | |
| SCHEMBL564497 | 0.72 | CA2 (0.45) | CA1CA2CA4KEAP1NFE2L2 | |
| SCHEMBL21148177 | 0.67 | CTSB (0.49) | CTSBHSD11B1 | |
| SCHEMBL10179600 | 0.66 | CTSB (0.45) | CTSBHSD11B1 | |
| SCHEMBL28539386 | 0.66 | MMP2 (0.49) | CYP2C19CA1CA2CTSBMMP2 | |
| Valine SCHEMBL8046877 | 0.65 | SLC7A5 (0.44) | CTSBKYNU | |
| Valine SCHEMBL8035352 | 0.65 | SLC7A5 (0.44) | CTSBKYNU | |
| SCHEMBL641321 | 0.65 | TDP1 (0.49) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL9218547 | 0.64 | APEX1 (0.62) | TSHRCTSBMMP2MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010080976-A1 | INSULIN THERAPIES FOR THE TREATMENT OF DIABETES, DIABETES RELATED AILMENTS, AND/OR DISEASES OR CONDITIONS OTHER THAN DIABETES OR DIABETES RELATED AILMENTS | SDG, INC. (AN OHIO CORPORATION) (US) | 2010-07-15 | — | — | WO | disclosed |