Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 16/20 | 0.42 |
| ▸ | CA2 | P00918 | 16/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423871 | 0.86 | KEAP1 (0.49) | KEAP1NFE2L2CA1CA2CA12 | |
| SCHEMBL564497 | 0.82 | CA2 (0.45) | KEAP1NFE2L2CA1CA2CA12 | |
| SCHEMBL3724960 | 0.80 | ALOX15 (0.42) | KEAP1NFE2L2CA1CA2CA4 | |
| SCHEMBL27767604 | 0.78 | GABBR2 (0.43) | CA1CA2CA12CA9CA4 | |
| SCHEMBL27560669 | 0.75 | MMP13 (0.44) | CA1CA2ALDH1A1 | |
| SCHEMBL27625448 | 0.73 | ALDH1A1 (0.41) | CA1CA2CA12CA9CA4 | |
| SCHEMBL8732760 | 0.71 | CA12 (0.44) | CA1CA2CA12CA9CA4 | |
| SCHEMBL28895074 | 0.70 | PSIP1 (0.50) | CA1CA2CA12CA9CA4 | |
| Hydrochloric Acid SCHEMBL29141929 | 0.70 | CA12 (0.43) | CA1CA2CA12CA9CA4 | |
| SCHEMBL453898 | 0.69 | KDM4E (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552202-A1 | METHODS AND COMPOSITIONS FOR WEIGHT LOSS | SDG, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011119953-A1 | METHODS AND COMPOSITIONS FOR WEIGHT LOSS | SDG, INC. (US) | 2011-09-29 | — | — | WO | disclosed |