Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | SCD | O00767 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13260110 | 0.91 | KDM4E (0.43) | HDAC1HDAC7SCDALDH1A1HDAC3 | |
| SCHEMBL3724975 | 0.80 | KDM4E (0.45) | HDAC1HDAC7SCDALDH1A1KMT2A | |
| SCHEMBL3721607 | 0.77 | KDM4E (0.43) | HDAC1HDAC7SCDALDH1A1L3MBTL1 | |
| SCHEMBL3725282 | 0.76 | KMT2A (0.41) | HDAC1HDAC7SCDALDH1A1KMT2A | |
| SCHEMBL3725017 | 0.75 | SCD (0.39) | HDAC1HDAC7SCDALDH1A1L3MBTL1 | |
| SCHEMBL3724448 | 0.75 | POLQ (0.41) | HDAC1HDAC7SCDALDH1A1HDAC3 | |
| SCHEMBL3722206 | 0.72 | POLQ (0.52) | L3MBTL1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL25243961 | 0.69 | HDAC1 (0.49) | HDAC1HDAC7SCDALDH1A1L3MBTL1 | |
| SCHEMBL3731459 | 0.68 | L3MBTL1 (0.51) | SCDL3MBTL1SCD5POLBKDM4E | |
| SCHEMBL3725838 | 0.68 | KDM4E (0.45) | HDAC1HDAC7SCDALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093885-A1 | INHIBITORS OF AKT ACTIVITY | GLAXOSMITHKLINE LLC (US) | 2010-08-19 | — | — | WO | disclosed |