Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701452 | 0.79 | — | — | |
| Sulfuric Acid SCHEMBL19285797 | 0.74 | TP53 (0.33) | TP53 | |
| SCHEMBL23827457 | 0.68 | — | — | |
| SCHEMBL23681 | 0.68 | — | — | |
| SCHEMBL92312 | 0.67 | — | — | |
| SCHEMBL28813431 | 0.67 | — | — | |
| SCHEMBL263198 | 0.66 | — | — | |
| SCHEMBL7753331 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL9421367 | 0.66 | — | — | |
| SCHEMBL13847596 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156766-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-20240139137-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CYDEX PHARMACEUTICALS, INC. | 2024-05-02 | — | — | US | disclosed |
| EP-4274561-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | Quadriga Biosciences, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20230348631-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-116847855-A | Pharmaceutical composition of chemotherapeutic agents based on beta-substituted beta-amino acid derivatives | 夸德里加生物科学公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022147743-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022148456-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | QUADRIGA BIOSCIENCES, INC. (US) | 2022-07-14 | — | — | WO | disclosed |
| US-20210379000-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2021-12-09 | — | — | US | disclosed |
| US-11020363-B2 | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same | CYDEX PHARMACEUTICALS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-10940128-B2 | Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same | CYDEX PHARMACEUTICALS, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-20210046033-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CYDEX PHARMACEUTICALS, INC. | 2021-02-18 | — | — | US | disclosed |
| US-10864183-B2 | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same | CYDEX PHARMACEUTICALS, INC. (US) | 2020-12-15 | — | — | US | disclosed |
| US-20200268698-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2020-08-27 | — | — | US | disclosed |
| EP-3100728-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PRASUGREL AND CYCLODEXTRIN DERIVATIVES AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS INC (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-2434886-B1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS INC (US) | 2019-10-16 | — | — | EP | disclosed |
| CN-106389307-A | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | 锡德克斯药物公司 | 2017-02-15 | — | — | CN | disclosed |
| US-20140221488-A1 | Injectable Melphalan Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CYDEX PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140213650-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CYDEX PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-20100311838-A1 | Injectable Melphalan Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | CYDEX PHARMACEUTICALS, INC. | 2010-12-09 | — | — | US | disclosed |
| WO-2010138920-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | CYDEX PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348631-A1 | PHARMACEUTICAL COMPOSITIONS OF CHEMOTHERAPEUTIC AGENTS BASED ON BETA-SUBSTITUTED BETA-AMINO ACID DERIVATIVES | BCAT1, BCAT2, DDC | TP53 27/4885 |
| US-10940128-B2 | Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same | MCL1, MYADM, IL2 | TP53 795/4885 |
| US-11020363-B2 | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same | GYS2, NOTUM, PYGL | TP53 1251/4885 |
| US-20200268698-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | GYS2, NOTUM, PYGL | TP53 1251/4885 |
| US-20100311838-A1 | Injectable Melphalan Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | MCL1, MYADM, IL2 | TP53 795/4885 |
| US-20140221488-A1 | Injectable Melphalan Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | MCL1, MYADM, IL2 | TP53 795/4885 |
| US-20210046033-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | GYS2, NOTUM, PYGL | TP53 1251/4885 |
| US-20210379000-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | MCL1, MYADM, IL2 | TP53 795/4885 |
| US-20240156766-A1 | INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAME | MCL1, MYADM, IL2 | TP53 795/4885 |
| US-10864183-B2 | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same | GYS2, NOTUM, PYGL | TP53 1251/4885 |
| US-20140213650-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | GYS2, NOTUM, PYGL | TP53 1251/4885 |
| US-20240139137-A1 | Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the Same | GYS2, NOTUM, PYGL | TP53 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.