Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725760 | 0.84 | GAA (0.48) | PKMNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL11822889 | 0.82 | KMT2A (0.53) | MAPK8RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL11830961 | 0.82 | ALDH1A1 (0.53) | MAPK8NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL21981000 | 0.81 | RAB9A (0.53) | MAPK8KCNJ5KCNJ3NPC1RAB9A | |
| SCHEMBL5458594 | 0.81 | GLS (0.49) | PKMMAPK8KCNJ5KCNJ3NPC1 | |
| SCHEMBL3725312 | 0.81 | P2RX7 (0.57) | NPC1RAB9AKMT2AALDH1A1ERCC1 | |
| SCHEMBL3729261 | 0.81 | MAPK8 (0.51) | MAPK8NPC1RAB9AKMT2AGAA | |
| SCHEMBL9527449 | 0.80 | NPC1 (0.55) | PKMMAPK8KCNJ5KCNJ3NPC1 | |
| SCHEMBL3728259 | 0.78 | ATM (0.65) | MAPK8KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL8636686 | 0.78 | MAPK8 (0.67) | MAPK8KCNJ5KCNJ3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
| US-3992396-A | TRANQUILIZERS, HYPNOTICS | SANDOZ, INC. (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | PKM 1419/4885MAPK8 3384/4885KCNJ5 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.