Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.42 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726420 | 0.90 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL3720294 | 0.84 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL3727288 | 0.84 | ACACB (0.46) | ACACBSTK39ESRRAACACA | |
| SCHEMBL3728857 | 0.77 | STK39 (0.41) | ACACBSTK39ESRRA | |
| SCHEMBL3798078 | 0.73 | ALOX5 (0.57) | ACACBACACA | |
| SCHEMBL3719663 | 0.73 | ACACB (0.56) | ACACBACACA | |
| SCHEMBL3719330 | 0.72 | ESRRA (0.60) | STK39ESRRA | |
| SCHEMBL3724748 | 0.72 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL3726987 | 0.71 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL3720744 | 0.71 | ACACB (0.51) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |