Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 9/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3733288 | 0.86 | L3MBTL1 (0.49) | SIGMAR1L3MBTL1GAAMAPK8GRIN2B | |
| SCHEMBL1474719 | 0.80 | SIGMAR1 (0.72) | SIGMAR1 | |
| SCHEMBL3734917 | 0.80 | DPP4 (0.38) | L3MBTL1DPP4DPP7DPP9DPP8 | |
| SCHEMBL243780 | 0.79 | ALDH1A1 (0.47) | SIGMAR1GAARAB9A | |
| SCHEMBL1477856 | 0.78 | SLC6A4 (0.47) | SIGMAR1L3MBTL1GAA | |
| SCHEMBL6858298 | 0.77 | CES2 (0.48) | SIGMAR1DPP4DPP7DPP9DPP8 | |
| SCHEMBL3744223 | 0.77 | P2RX7 (0.39) | RIPK1CES2CES1 | |
| SCHEMBL29471363 | 0.76 | TSHR (0.53) | SIGMAR1MAPK8RIPK1CES2CES1 | |
| SCHEMBL503667 | 0.76 | TSHR (0.53) | SIGMAR1MAPK8RIPK1CES2CES1 | |
| SCHEMBL28061383 | 0.76 | CES2 (0.47) | SIGMAR1DPP4DPP7DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829580-B2 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20060270706-A1 | Cyclic amine derivative having heteroaryl ring | SANKYO COMPANY, LTD. (JP) | 2006-11-30 | — | — | US | disclosed |
| EP-1695962-A1 | CYCLIC AMINE DERIVATIVE HAVING HETEROARYL RING | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270706-A1 | Cyclic amine derivative having heteroaryl ring | F12, F2, H1-3 | SIGMAR1 262/4885L3MBTL1 926/4885GAA 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.