Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 14/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 11/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 11/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CFB | P00751 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723548 | 0.81 | ADRA2B (0.84) | ADRA2AADRA2BADRA2CADRA1AMAOA | |
| SCHEMBL10558644 | 0.74 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL2215147 | 0.74 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CADRA1ATRPV1 | |
| SCHEMBL2216731 | 0.74 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1ATRPV1 | |
| SCHEMBL1724062 | 0.73 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1ATSHR | |
| SCHEMBL23138723 | 0.72 | PDPK1 (0.59) | TRPV1IDO1MAOAMAOB | |
| SCHEMBL4057043 | 0.70 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1AGMNN | |
| SCHEMBL4054961 | 0.69 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CADRA1ATRPV1 | |
| SCHEMBL11960137 | 0.68 | PFKFB3 (0.37) | TRPV1IDO1MAOAMAOB | |
| SCHEMBL11960083 | 0.68 | PFKFB3 (0.37) | TRPV1IDO1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100280085-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| EP-2048951-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008017816-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280085-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, COX6B1 | ADRA2A 2634/4885ADRA2B 2755/4885ADRA2C 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.