SCHEMBL3742298

SCHEMBL3742298

O=C(O)C1CC(O)C(O)CC1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.50
SLC1A2 P43004 3/20 0.50
LMNA P02545 3/20 0.50
CYP2C19 P33261 2/20 0.50
PMP22 Q01453 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP2C9 P11712 1/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
APEX1 P27695 1/20 0.50
GRM5 P41594 1/20 0.50
GRM1 Q13255 1/20 0.50
GRM2 Q14416 1/20 0.50
GRM3 Q14832 1/20 0.50
GRM4 Q14833 1/20 0.50
KDM4E B2RXH2 1/20 0.50
SLC1A1 P43005 2/20 0.48
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4083282 1.00 GABRR1 (0.50) GABRR1SLC1A2LMNACYP2C19PMP22
SCHEMBL10476744 1.00 GABRR1 (0.50) GABRR1SLC1A2LMNACYP2C19PMP22
SCHEMBL14503133 1.00 GABRR1 (0.50) GABRR1SLC1A2LMNACYP2C19PMP22
SCHEMBL4083394 1.00 GABRR1 (0.50) GABRR1SLC1A2LMNACYP2C19PMP22
SCHEMBL10476678 1.00 GABRR1 (0.50) GABRR1SLC1A2LMNACYP2C19PMP22
SCHEMBL3742301 1.00 GABRR1 (0.50) GABRR1SLC1A2LMNACYP2C19PMP22
SCHEMBL12276963 0.87 GABRR1 (0.50) GABRR1SLC1A2LMNACYP2C19PMP22
SCHEMBL28265022 0.84
SCHEMBL28934977 0.83
SCHEMBL6580400 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230118-A1 TWO-STAGE PROCESS FOR PRODUCING TETRAALKYL 1,2,3,4 BUTANETETRACARBOXYLATES EVONIK OXENO GMBH & CO. KG (DE) 2025-07-17 US disclosed
US-11149202-B1 Tetracarboxylic acid combinations for corrosion inhibition ECOLAB USA INC. (US) 2021-10-19 US disclosed
US-11149202-B1 Tetracarboxylic acid combinations for corrosion inhibition ECOLAB USA INC. (US) 2021-10-19 US disclosed
EP-2431370-B1 Monoacylated 1,2-diaminocycloalkanes DAIICHI SANKYO CO LTD (JP) 2013-06-19 EP disclosed
EP-1270557-B1 ETHYLENEDIAMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2012-07-25 EP disclosed
CN-101166709-B Process for preparing tetracarboxylic acids BASF AG 2011-03-30 CN disclosed
US-7834211-B2 Method for producing tetracarboxylic acids BASF AKTIENGESELLSCHAFT (DE) 2010-11-16 US disclosed
US-20090227789-A1 ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2009-09-10 US disclosed
US-20090124827-A1 Method For Producing Tetracarboxylic Acids BASF AKTIENGESELLSCHAFT (DE) 2009-05-14 US disclosed
EP-1877358-B1 METHOD FOR PRODUCING TETRACARBOXYLIC ACIDS BASF SE (DE) 2008-12-17 EP disclosed
CN-101166709-A Process for preparing tetracarboxylic acids BASF AG (DE) 2008-04-23 CN disclosed
EP-1877358-A1 METHOD FOR PRODUCING TETRACARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 2008-01-16 EP disclosed
US-7192968-B2 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-03-20 US disclosed
WO-2006117326-A1 METHOD FOR PRODUCING TETRACARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 2006-11-09 WO disclosed
US-20060004009-A1 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
US-20040122063-A1 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-24 US disclosed
EP-1270557-A1 ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-01-02 EP disclosed
US-5157152-A Process for the oxidation of a tetrahydrophthalic acid ORTEC, INC. (US) 1992-10-20 US disclosed
US-5047582-A Process for the oxidation of a tetrahydrophthalic acid ORTEC, INC. (US) 1991-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230118-A1 TWO-STAGE PROCESS FOR PRODUCING TETRAALKYL 1,2,3,4 BUTANETETRACARBOXYLATES ADH1A, ADH1C, TBCA GABRR1 1301/4885SLC1A2 2209/4885LMNA 1610/4885
US-20060004009-A1 Ethylenediamine derivatives F2, ECE1, MLLT1 GABRR1 4000/4885SLC1A2 2591/4885LMNA 814/4885
US-11149202-B1 Tetracarboxylic acid combinations for corrosion inhibition CA1, TMCO1, CTRC GABRR1 1450/4885SLC1A2 2279/4885LMNA 3560/4885
US-20090124827-A1 Method For Producing Tetracarboxylic Acids CBR1, AOC2, NOS2 GABRR1 864/4885SLC1A2 2170/4885LMNA 2083/4885
US-20090227789-A1 ETHYLENEDIAMINE DERIVATIVES F2, ECE1, MLLT1 GABRR1 4000/4885SLC1A2 2591/4885LMNA 814/4885
US-20040122063-A1 Ethylenediamine derivatives ECE1, F2, ECE2 GABRR1 3036/4885SLC1A2 2255/4885LMNA 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.