Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.34 |
| ▸ | ACP1 | P24666 | 3/20 | 0.34 |
| ▸ | CDC25B | P30305 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239526 | 0.93 | ACHE (0.43) | TDP1L3MBTL1ACHEBACE1PTPN1 | |
| SCHEMBL23934182 | 0.76 | CYP2C9 (0.39) | TDP1L3MBTL1PTPN1CYP1A2CYP2C19 | |
| SCHEMBL11220616 | 0.75 | ACHE (0.45) | ACHEBACE1PTPN1ACP1CDC25B | |
| SCHEMBL3242954 | 0.64 | ALDH1A1 (0.35) | TDP1L3MBTL1PTPN1ACP1CDC25B | |
| SCHEMBL234448 | 0.64 | ACHE (0.40) | ACHEBACE1PTPN1CDC25BCTRC | |
| SCHEMBL4278987 | 0.63 | CYP19A1 (0.37) | ACHEBACE1ALDH1A1 | |
| SCHEMBL27516481 | 0.63 | ACHE (0.42) | ACHEBACE1PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL5588331 | 0.63 | ACHE (0.42) | ACHEBACE1PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL6361888 | 0.63 | STAT3 (0.58) | TDP1ACHEBACE1PTPN1ALDH1A1 | |
| SCHEMBL364755 | 0.63 | GPR84 (0.37) | ACHEBACE1PTPN1KMT2ACTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | TAS2R5, TAS2R1, TAS1R1 | TDP1 3583/4885L3MBTL1 2316/4885ACHE 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.